Results 151 to 160 of about 16,807,593 (396)

The effect of tube diameter on vertical two-phase flow regimes in small tubes [PDF]

open access: yes, 2006
Flow boiling flow patterns in four circular tubes with internal diameters of 1.10, 2.01, 2.88 and 4.26 mm were investigated in the present project. The experiments were conducted in vertical upward two-phase flow using R134a as the working fluid.
Chen, L, Karayiannis, TG, Tian, YS
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Tame flows

open access: yesMemoirs of the American Mathematical Society, 2010
The tame flows are ``nice'' flows on ``nice'' spaces. The nice (tame) sets are the pfaffian sets introduced by Khovanski, and a flow $ : \mathbb{R}\times X\to X$ on pfaffian set $X$ is tame if the graph of $ $ is a pfaffian subset of $\mathbb{R}\times X\times X$. Any compact tame set admits plenty tame flows.
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Reduced coupling between cerebrospinal fluid flow and global brain activity is linked to tau pathology [PDF]

open access: bronze, 2023
Feng Han   +7 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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