Results 51 to 60 of about 2,565,967 (267)

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Small-width wall-attached Coandǎ jets for flow control

open access: yesFlow, 2023
The flow dynamics of small-width wall-attached jets generated by a Coand-effect nozzle is investigated by unsteady Reynolds-averaged Navier–Stokes simulations. The data are validated by comparison with hot-wire velocity measurements performed on the same
Oussama El Mokkadem   +6 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Uniformly distributed floor sources of buoyancy can give rise to significant spatial inhomogeneities within rooms

open access: yesFlow, 2023
Displacement ventilation, where cool external air enters a room through low-level vents and warmer air leaves through high-level vents, is characterised by vertical gradients in pressure arising from the warmer indoor temperatures.
Carolanne V.M. Vouriot   +5 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Neural prediction model for transition onset of a boundary layer in presence of two-dimensional surface defects

open access: yesFlow, 2023
Predicting the laminar to turbulent transition is an important aspect of computational fluid dynamics because of its impact on skin friction. Traditional transition prediction methods such as local stability theory or the parabolized stability equation ...
Adrien Rouviere   +4 more
doaj   +1 more source

Analysis of Flow Meters Calibration [PDF]

open access: yes, 2015
Calibration data of flow meters are often reported using the so called calibration coefficient, i.e. the ratio between the reference flow rate (or equivalent quantity, e.g.
SPAZZINI, PIER GIORGIO   +3 more
core  

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Adaptive drag reduction of a sphere using smart morphable skin

open access: yesFlow
In this study, a novel smart surface-morphing technique is devised that dynamically optimises roughness parameter on a sphere with varying flow conditions to minimise drag. A comprehensive series of experiments are first performed to systematically study
Rodrigo Vilumbrales-Garcia   +2 more
doaj   +1 more source

Measurements and scaling of buoyancy-induced flows in ventilated tunnels

open access: yesFlow, 2023
We investigate the ventilation conditions required to control the propagation of smoke, produced by a tunnel fire, in the presence of two inertial forcings: a transverse extraction system and a longitudinal flow.
Pietro Salizzoni   +6 more
doaj   +1 more source

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