Results 151 to 160 of about 834,813 (315)
CHARACTERISTICS OF TURBULENT FLOW
Turbulent flow is a complex and chaotic movement of fluid that occurs when a fluid moves at high velocities or interacts with solid boundaries. This phenomenon is critical in a wide range of scientific and engineering applications, such as in weather systems, industrial processes, and aerodynamics.
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Two-grid Characteristic Finite Element Method for Incompressible Flow [PDF]
This study proposes and briefly analyzes a two-grid characteristic finite element method based on a residual technique, with the low order pair of mixed finite element such as P1−P1, for the incompressible time-dependent Navier–Stokes equations.
Qin, Junchang, He, Xiaoming, Jiang, Yu
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Numerical study of high speed separated flows [PDF]
, 2014 Instability, flow separation and transition are essential aspects of high speed flows with shock-wave/boundary-layer interaction. Supersonic flows with jet injection, compression ramp and cavity, either individually or in combination, are numerically ...
Zhang, Kangping
core
Characteristics of Cavity Flow at Different Reynolds Numbers
工程科学与技术, 2013 :This study focuses on influence of Reynolds number on characteristics of cavity flow using Particle Image Velocimetry (PIV). Results show that time-mean velocity fields display same structures at different Reynolds numbers, namely, main flow and ...
Chen Huai
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Two-phase flow boiling in small to micro-diameter tubes [PDF]
, 2008 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis is dedicated to the experimental and theoretical study of flow boiling in small to micro diameter tubes using R 134a.
Shiferaw, Dereje
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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