Results 81 to 90 of about 5,222,192 (298)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Numerical analysis of viscid compressible ionic flow [PDF]

open access: yes, 2006
The aim of the paper is to investigate numerically the effect of a DC positive corona discharge between two parallel wire electrodes of different diameter along an insulating aerofoil surface in low subsonic compressible flow.
Tulita, C.   +3 more
core   +1 more source

DETERMINATION OF THE FLOW CHARACTERISTIC OF A HIGH-ROTATIONAL CENTRIFUGAL PUMP BY MEANS OF CFD METHODS

open access: yesTASK Quarterly, 2008
The paper refers to a numerical analysis of the flow through a centrifugal pump working at high rotational speed. This kind of a pump is characterized by a high delivery head and a low discharge.
SŁAWOMIR DYKAS, ANDRZEJ WILK
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Validation of CFD Analysis on Flow and Combustion Characteristics for a GP3 Rotary Engine

open access: yesEnergies
This study performed a 3D CFD analysis on a GP3 rotary engine to determine the stroke and flow characteristics and examine the thermal- and flow-related design factors’ validity. The 3D CFD analysis was performed using the CONVERGE program, utilizing the
Young-Jic Kim, A-Sun Yoon, Chang-Eon Lee
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Speed Anticipation Characteristic with Optical Flow for Driver Behavior Assessment of Older Drivers [PDF]

open access: yes, 2019
The objective of this study is to clarify the relationship between the speed anticipation characteristic with optical flow derived from self-motion and driver behavior of older drivers for future driver assessment.
Shino, Motoki   +5 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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