Results 151 to 160 of about 2,574,025 (316)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Addressing information flow in lean production management and control in construction
, 2014 Traditionally, production control on construction sites has been a challenging area, where the ad-hoc production control methods foster uncertainty - one of the biggest enemies of efficiency and smooth production flow.
Kubler, Silvain +3 more
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Optimization Methods Applied to Aerodynamic Flow Control [PDF]
, 2012 International audienceThis study deals with the use of optimization algorithms to determine efficient param- eters of flow control devices. To improve the performance of systems characterized by detached flows and vortex shedding, the use of flow control
Labroquère, Jérémie +1 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Effect of vasomotion on blood flow distribution in microvessels
3rd Symposium on Flow-Structure-Sound Interactions and Control (FSSIC), 6th to 9th July, 2015, Perth, Western Australia202405 bcchAccepted ManuscriptRGCPublishedGreen ...
Shao, JC, Liu, Y, Su, ZD
core +1 more source
Analysis and control of resonant cavity flows [PDF]
, 2013 Recently, the trend for the internalisation of stores within an aircraft fuselage has led to a renewed interest in the field of cavity aero-acoustics.
Roberts, David
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Plasma based jet actuators for flow control
, 2012 A set of plasma based jet actuators were designed for flow control applications. The characteristics of these actuators and their flow control applications were studied experimentally in a low speed wind tunnel.A dielectric barrier discharge (DBD) based ...
Luo, Xinfu
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source