Results 131 to 140 of about 2,292,052 (266)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Flow control of three-dimensional cylinders transitioning to turbulence via multi-agent reinforcement learning. [PDF]

open access: yesCommun Eng
Suárez P   +6 more
europepmc   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Safety and lesion characteristics of temperature-flow control vs power control modes in radiofrequency ablation: An in vivo study in swine. [PDF]

open access: yesHeart Rhythm O2
Xia P   +11 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Transarterial Embolization for Dural Arteriovenous Fistula Using a Flow-Control Technique and Intraluminal Shunt. [PDF]

open access: yesNeurosurg Pract
Yoshida K   +6 more
europepmc   +1 more source

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