Results 111 to 120 of about 14,345,300 (303)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Fluid Flow Control: a Vision-Based Approach [PDF]
, 2011 International audienceThis paper proposes a new approach to control a flow. Controlling a flow consists either to change its state to another state or to maintain its current state whatever external disturbances.
Collewet, Christophe +1 more
core +1 more source
Hypersonic flow control using magneto-hydrodynamics [PDF]
, 2008 The focus of the present work is on the use of magneto hydrodynamics as a flow control device for supersonic and hypersonic vehicles. A three dimensional parabolized Navier Stokes solver was developed to take into account the effects of magnetic ...
Bennett, J. S.
core +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Advanced Materials InterfacesDroplets constitute an essential discrete form of liquids and are prevalent in both natural and industrial fields. Droplet manipulation technologies have broad application prospects in various fields, including biomedical devices, chemical engineering ...
Xinyuan Liu +6 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
ActuatorsAn adaptive particle refinement (APR) algorithm has been developed for the smoothed particle hydrodynamics (SPH) method to augment the resolution of the region of interest to achieve high accuracy and simultaneously reduce the cost of computational ...
Jun Zhang +5 more
doaj +1 more source
Active Flow Separation Control on a High-Lift Wing-Body Configuration. Part 2: The Pulsed Blowing Application. [PDF]
, 2011 This contribution discusses the implementation of active flow separation control for a 3D high-lift wing-body configuration under atmospheric low-speed wind tunnel conditions.
Rudnik, Ralf +4 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source