Results 101 to 110 of about 6,124,378 (340)

Erratum:In SituControl of Gas Flow by Modification of Gas-Solid Interactions [Phys. Rev. Lett. 111, 174502 (2013)] [PDF]

, 2014
Dongjin Seo, William A. Ducker
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Numerical Investigation of the Coupling Effects of Pulsed H₂ Jets and Nanosecond-Pulsed Actuation in Supersonic Crossflow

Aerospace
Numerical investigations were conducted to analyze the coupling effects of pulsed H2 jets and nanosecond-pulsed actuation (NS-SDBD) in a supersonic crossflow.
Keyu Li, Jiangfeng Wang
doaj   +1 more source

Flexible parylene actuator for micro adaptive flow control [PDF]

, 2001
This paper describes the first flexible parylene electrostatic actuator valves intended for micro adaptive flow control for the future use on the wings of micro-air-vehicle (MAV).
Ho, C. M., Nassef, H., Pornsin-Sirirak, T. N., Tai, Y. C.   +3 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Experiments of Lift-Bending Response on a Slender UAV Wing Structure with Control Surface under Extreme Flow Turbulence

Aerospace
The aeroelastic response of lightweight low-speed aircrafts with slender wings under extreme flow turbulence intensity is not well understood. Experiments on a commercial unmanned aerial vehicle (UAV) with a 3 m wingspan and aspect ratio of 13.6 were ...
Wolduamlak Ayele, Victor Maldonado, Siva Parameswaran   +2 more
doaj   +1 more source

Microfluidic droplet control by photothermal interfacial flow [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Motosuke, M, Muto, M   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Experimental Study of Mechatronic System On Control of Air Flow Temperature

, 2022
Asmara Yanto, Adriyan Adriyan, Rozi Saferi, Muhammad Hafizh   +3 more
openalex   +2 more sources