Results 91 to 100 of about 2,034,998 (303)
Priority-Based Data Flow Control for Long-Range Wide Area Networks in Internet of Military Things
Journal of Sensor and Actuator NetworksThe Internet of Military Things (IoMT) is transforming defense operations by enabling the seamless integration of sensors and actuators for the real-time transmission of critical data in diverse military environments.
Rachel Kufakunesu +2 more
doaj +1 more source
Deep model predictive flow control with limited sensor data and online learning [PDF]
, 2020 Katharina Bieker +4 more
openalex +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Performance measurements of mixed data acquisition and LAN traffic on a credit-based flow-controlled ATM network [PDF]
, 1998 M. Nomachi +4 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Information-flow-based Access Control for Virtualized Systems
Безопасность информационных технологий, 2014 The article is devoted to the method of information-flow-based access control, adopted for virtualized systems. General structure of access control system for virtual infrastructure is proposed.
Dmitriy Aleksandrovich Postoev
doaj
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Enhancing Data Flow Tracking for Data Usage Control
, 2020 This thesis provides a new, hybrid approach in the field of Distributed Data Usage Control (DUC), to track the flow of data inside applications. A combination between static information flow analysis and dynamic data flow tracking enables to track selectively only those program locations that are actually relevant for a flow of data.
openaire +1 more source