Results 91 to 100 of about 9,778,559 (291)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Multi-Year eDNA Metabarcoding Reveals Fish Community Dynamics in the Jiangsu Section of the Yangtze River Mainstem Under the Fishing Ban

open access: yesDiversity
Environmental DNA (eDNA) metabarcoding is an efficient, non-invasive approach for surveying fish diversity in complex habitats such as large rivers. This study conducted continuous eDNA monitoring along the Jiangsu section of the Yangtze River mainstem ...
Yinhua Wang   +5 more
doaj   +1 more source

On parametric evenness measures

open access: yes, 2003
The degree to which abundances are divided equitably among community species or evenness is a basic property of any biological community. Several evenness indices have thus far been proposed in ecological literature.
RICOTTA, Carlo, Carlo Ricotta
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Precipitation regime drives key alterations in subtropical stream fish community assembly and functional trait distribution across a major rainfall gradient

open access: yesJournal of Freshwater Ecology
Shifting precipitation patterns associated with global climate change are significantly impacting lotic ecosystems worldwide. To understand how these changes influence stream fish community assembly, we conducted a space-for-time study under a steep ...
Christopher M. Groff   +12 more
doaj   +1 more source

On the mutual relatedness of evenness measures [PDF]

open access: yes, 2001
Several evenness measures have been proposed for quantifying the distribution of abundance among community species, but none seems to be generally preferred.
AVENA, Giancarlo   +10 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Composition and diversity pattern of plant community with elevational gradient in Yuanjiang dry-hot valley

open access: yesGuangxi Zhiwu
Although dry-hot valleys in Southwest China have shaped a landscape with a vegetation appearance similar to that of African savannas, they are different from the African savannas because of the vertical geomorphology and climate type formed by the depth ...
LI Zhenxue1, DAO Zhigang1, ZHAO Gaojuan2,3*, CHEN Chao4, ZHANG Shubin2,3, ZHANG Chunzao1, LI Shouqi1, WEN Handong4, LI Tianliang4, CHEN Yajun2,3,4
doaj   +1 more source

A new index measuring evenness [PDF]

open access: yes, 1974
A new evenness index based on the Shannon-Wiener information H is defined as (eH -1)/(S -1).
Heip, C.H.R., C. Heip
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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