Results 101 to 110 of about 9,778,559 (291)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Efficient and Low-Loss Cleaning Method for Non-Uniform Distribution of Threshed Materials Based on Multi-Wing Curved Combination Air Screen in Computational Fluid Dynamics/Discrete Element Method Simulations

open access: yesAgriculture
During the operation of the longitudinal axis flow threshing device of a combine harvester, the threshed materials form accumulations and blockages on both sides of the screen surface, severely affecting the harvesting process.
Longhai Wang   +4 more
semanticscholar   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Distribution Characteristics of Heavy Metals in Sediments and Their Relationship with Benthic Fauna in the Clam Mudflat Aquaculture Area of Rudong, Jiangsu Province, China

open access: yesProgress in Fishery Sciences
Mudflats, located at the land-sea interface, are extremely rich in ecological resources. They are an important spatial carrier for human survival and development and are notably influenced by human activities. The rapid social and economic development of
Haopeng HU   +5 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

The effects of different distributor head types, air velocities and fertilizing rates on flow evenness for some fertilizers

open access: yes, 2010
In this study, three different types of distributor head (T, funnel and Y) were tested at three air velocities of 26, 31 and 36 ms(-1), and three different fertilizing rates were selected as 12, 16 and 20 kg da(-1) for two different fertilizers having ...
Guler, Ibrahim Ethem
core  

Seed Flow and In-row Seed Distribution Uniformity of the Top Delivery Type Fluted Roller for Onion, Carrot and Canola Seeds [PDF]

open access: yes, 2011
WOS: 000304318900002In this study, seed flow rate, seed flow evenness and in-row seed distribution uniformity of top delivery normal type straight fluted roller were examined in the laboratory experiments for the random seeding of uncoated onion, carrot,
Onal, Ismet, Ertugrul, Omer
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Relationship between evenness and body size in species rich assemblages

open access: yes, 2013
Evenness is a key measure of community structure. Here, we examine the relationship between evenness and size-abundance distributions for both individuals and species using data gathered from Amazonian fish assemblages. We show that evenness increases as
A. P. Hercos   +6 more
core   +1 more source

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