Results 111 to 120 of about 4,414,012 (305)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Metals, 2018 The tundish with heating instrumentation is attracting more and more attention in continuous casting processes for maintaining a pre-determined constant pouring temperature under a given casting speed, which is beneficial for an improved and consistent ...
Haiyan Tang +5 more
doaj +1 more source
Turbine stator flow field simulations [PDF]
The increased capability and accessibility of modern computers, coupled with increasingly sophisticated and accurate numerical and physical modeling, has led to a marked impact of numerical simulations upon current turbine design and research problems ...
Briley, W. R. +3 more
core +1 more source
Characteristics of ion flow in the quiet inner plasma sheet [PDF]
, 1993 We use AMPTE/IRM and ISEE 2 data to study the properties of the high beta (βi \u3e 0.5) plasma sheet, the inner plasma sheet (IPS). Bursty bulk flows (BBFs) are excised from the two databases, and the average flow pattern in the non-BBF (quiet) IPS is ...
Angelopoulos, V. +10 more
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The disappearance of viscous and laminar wakes in complex flows [PDF]
, 2002 The singular effects of steady large-scale external strain on the viscous wake generated by a rigid body and the overall flow field are analysed. In an accelerating flow strained at a positive rate, the vorticity field is annihilated owing to positive ...
Eames, I, Hunt, JCR
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
MetalsSubmerged entry nozzle (SEN) clogging will affect the production efficiency and product quality in the continuous casting process. In this work, the transient SEN clogging model is developed by coupling the porous media model defined by the user-defined ...
Yuntong Li +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source