Results 71 to 80 of about 4,414,012 (305)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A CFD technique for estimating the flow distortion effects on LiDAR measurements when made in complex flow fields [PDF]

, 2013
The effect of flow distortion on the measurements produced by a LiDAR or SoDAR in close proximity to either complex terrain or a structure creating localised flow distortion is difficult to determine by analytical means.
Astrup, P., Fabre, Sylvie, Mikkelsen, Torben, Oldroyd, Andrew, Scanlon, Thomas, Stickland, Matthew   +5 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Impact of the gap distance between two adjacent external windshields of a high-speed train on surrounding flow characteristics: an IDDES study

Engineering Applications of Computational Fluid Mechanics, 2022
The external windshield is a key component in high-speed trains for drag reduction. However, the installation gap between external windshields, which is intended for improving curve-passing ability, could lead to strong aerodynamic instability in train ...
Fan Cheng, Xiao-Hui Xiong, Ming-Zan Tang, Xiao-Bai Li, Xin-Ran Wang   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Influence of spool diffusion profile on flow characteristics of turbine control valve

Zhongguo Jianchuan Yanjiu
ObjectiveTo address the operational instability, vibration, and abnormal noise in a specific steam turbine unit, this study proposes a method for modifying the internal flow characteristics of the control valve through an internally-cut valve core ...
Luotao XIE, Yuang SHI, Jingtao WANG, Ziyi ZOU, Zhifang FEI, Guobing CHEN, Lei ZHANG   +6 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Flow Velocity Distribution Downstream of Nanofibrous Filter in Minichannel Determined by Particle Image Velocimetry Method

Applied Sciences
The paper presents the results of investigations of flow velocity field distribution downstream of the nanofibrous filter in a minichannel determined by the particle image velocimetry (PIV) method.
Andrzej Krupa, Izabela Wardach-Święcicka, Karol Ronewicz, Anatol Jaworek   +3 more
doaj   +1 more source

Transport of magnetic field by a turbulent flow of liquid sodium

, 2006
We study the effect of a turbulent flow of liquid sodium generated in the von K\'arm\'an geometry, on the localized field of a magnet placed close to the frontier of the flow.
A. Chiffaudel, B. Lehnert, F. Daviaud, F. Krause, F. Pétrélis, F. Ravelet, H. K. Moffatt, J.-F. Pinton, M. Berhanu, N. Mordant, P. H. Roberts, Ph. Odier, R. Monchaux, R. Volk, S. Fauve, S. Fauve, Ya. B. Zeldovich   +16 more
core   +3 more sources