Results 41 to 50 of about 598,469 (307)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Three-dimensional Flow Field Characteristics of a Normal Slot Plasma Synthetic Jet Actuator [PDF]

open access: yes
In this work, to comprehensively analyze the flow field characteristics of a normal slot plasma synthetic jet actuator, three-dimensional simulation models are established for both normal slot and normal orifice actuators. A detailed comparative analysis
X. L. Sun, S. Ma, L. Cheng
core   +1 more source

Research on Air-Flow-Field Characteristics and Structural Optimization of the Guide Channels of the Autoclave

open access: yes, 2022
In order to solve the problem of uneven air inlet flow in the guide channel of autoclave, three optimization schemes for the guide plate were proposed.
Yanan Sun   +7 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Numerical Study on the Operational Ventilation Patterns of Alternative Jet Fans in Curved Tunnels

open access: yesBuildings
In tunnel operation ventilation systems, the arrangement of jet fans plays a decisive role in ensuring ventilation efficiency. Curved tunnels, due to their unique radius of curvature, exhibit significant differences in fan installation parameters and jet
Li-Ming Wu   +6 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Effects of the Centrifugal Pump Outlet Blade Angle on Its Internal Flow Field Characteristics under Cavitation Condition [PDF]

open access: yes, 2022
The outlet blade angle is a key geometrical parameter that governs how the impeller directly influences centrifugal pump performance. Therefore, a reasonable angle selection is crucial.
W. G. Zhao   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy