Results 41 to 50 of about 68,920 (314)
Investigation of Post-Darcy Flow in Thin Porous Media
, 2021 We present numerical simulations of post-Darcy flow in thin porous medium: one consisting of staggered arrangements of circular cylinders and one random distribution of cylinders bounded between walls. The simulations span a range of Reynolds numbers, 40
Fallahjoybari, Nima +4 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A projection method for porous media flow
CoRR, 2022 16 pages, 3 ...
Nicholas J. Derr, Chris H. Rycroft
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
On the measurement of solute concentrations in 2-D flow tank experiments [PDF]
, 2007 In this study we describe and compare photometric and resistivity measurement methodologies to determine solute concentrations in porous media flow tank experiments.
E. Meier +11 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Geofluids, 2020 The successful development of tight oil reservoirs in the U.S. shows the bright future of unconventional reservoirs. Tight oil reservoirs will be the main target of exploration and development in the future, and CO2 huff-n-puff is one of the most ...
Yong Tang +6 more
doaj +1 more source
Transient flows in active porous media [PDF]
Physical Review E, 2017 Stimuli-responsive materials that modify their shape in response to changes in environmental conditions -- such as solute concentration, temperature, pH, and stress -- are widespread in nature and technology. Applications include micro- and nanoporous materials used in filtration and flow control.
Kosmidis, Lefteris I. +1 more
openaire +3 more sources
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Gas flow regimes judgement in nanoporous media by digital core analysis
Open Physics, 2018 A method to judge shale gas flow regimes based on digital core analysis is proposed in this work. Firstly, three-dimensional shale digital cores in an anonymous shale formation in the Sichuan Basin are reconstructed by a Markov Chain Monte Carlo (MCMC ...
Song Wenhui +7 more
doaj +1 more source