Results 111 to 120 of about 3,868,108 (302)

An experimental approach to heat loss measurement of horizontal two-phase flow boiling in low-pressure low-flow (LPLF) conditions

Case Studies in Thermal Engineering
A crucial parameter remarkably influencing the reliability and accuracy of vapor quality measurements in flow boiling experiments is the measurement of heat loss.
Mehdi Kabir
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Preliminary core-engine noise abatement experimental results of a fluid injection nozzle on a JT-15D turbofan engine [PDF]

Jet noise, as induced by shear stress, in an jet exhaust is investigated. Experiments were performed on a JT-15D fan jet to verify the inward momentum stress reduction concept.
Cheng, D. Y., Wang, P.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Hydraulic characteristics of pilot distributaries in the Mirpurkhas, Sanghar and Nawabshah districts, Sindh, Pakistan [PDF]

Discharge frequency / Hydraulics / Flow / Water loss / Seepage / Water distribution / Pakistan / Sindh / Mirpurkhas / Sanghar ...
Lashari, B., Siddiqui, R., Skogerboe, G. V.   +2 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Mechanism of irreversible energy loss in impeller of contra-rotating axial fan

Meitan xuebao
With the urgent need of energy saving and consumption reduction in today's world, the topic of increasing the energy conversion efficiency of ventilation fans has been attracted a lot of attentions, it has become a key issue in the field of ventilation ...
Yongping CHEN, Ronghua LIU, Shiqiang CHEN, Shixian WU, Dong LIU, Yangyi LI, Wenqing PENG   +6 more
doaj   +1 more source

An experimental trace gas investigation of fluid transport and mixing in a circular-to-rectangular transition duct [PDF]

An ethylene trace gas technique was used to map out fluid transport and mixing within a circular to rectangular transition duct. Ethylene gas was injected at several points in a cross stream plane upstream of the transition duct.
Hingst, W. R., Okiishi, T. H., Reichert, B. A.   +2 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Energy efficient engine diffuser/combustor model technology [PDF]

A full scale, full annular diffuser/combustor model test rig was tested to investigate how configurational changes affect pressure loss and flow separation characteristics.
Gardner, W.
core   +1 more source