Results 41 to 50 of about 67,359 (316)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Numerical study of nano-biofilm stagnation flow from a nonlinear stretching/shrinking surface with variable nanofluid and bioconvection transport properties

Scientific Reports, 2021
A mathematical model is developed for stagnation point flow toward a stretching or shrinking sheet of liquid nano-biofilm containing spherical nano-particles and bioconvecting gyrotactic micro-organisms.
Abdulaziz Alsenafi, O. Anwar Bég, M. Ferdows, Tasveer A. Bég, A. Kadir   +4 more
doaj   +1 more source

High-Level Thinking and TPACK of Pre-Service Mathematics Teachers in the 21st Century Learning

Edumatica: Jurnal Pendidikan Matematika, 2021
In the 21st century, learning requires high-level thinking processes and mastery of technology. The benefits of using technology accompanied by high-level thinking include 1) having many alternative solutions to problems, 2) be a good co-worker, and 3 ...
Wanda Nugroho Yanuarto, Anton Jaelani
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Academic self-efficacy and teacher social support as predictors of academic flow mathematics among senior high school students in Jambi City

Journal of Indonesian Psychological Science
Many senior high school students face challenges in situations that require mathematical skills, often resulting in low interest and discomfort in learning mathematics. This study aims to examine the influence of academic self-efficacy and teacher social
Auliya Ramadhanti, Kartika Nur Fathiyah, Rahman Pranovri Putra   +2 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

The influence of flow experience on mathematical creativity among primary school students in China

Frontiers in Education
IntroductionMathematical creativity refers to personal ability to propose novel and original solutions or ideas in the process of solving mathematical problems.
Xueshen Wang, Piriya Somasundram, Jingxian Zhang   +2 more
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Scale Formation on HSLA Steel during Continuous Casting Part II: The Effect of Surface Conditions

Metals, 2020
The present research addresses the effect of surface condition on oxide scale formation at high temperatures such as those experienced during secondary cooling in Continuous Casting.
Rosa Maria Pineda Huitron, Pavel Ernesto Ramírez López, Esa Vuorinen, Pooria Nazen Jalali, Leonardo Pelcastre, Maija Kärkkäinen   +5 more
doaj   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source