Results 81 to 90 of about 5,766,109 (191)

ANALYSIS OF FLOWING FLUID EFFECT ON FLOW AVERAGING TUBE

open access: yesTASK Quarterly, 2008
This paper presents a mathematical model and results of numerical simulations for a fluid flow around a flow averaging tube. The calculations have been performed using the commercially available FLUENT software.
MIROSŁAW KABACIŃSKI   +2 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Overview of anisotropic flow measurements from ALICE

open access: yesEPJ Web of Conferences, 2016
Anisotropic flow is an important observable to study the properties of the hot and dense matter, the Quark Gluon Plasma (QGP), created in heavy-ion collisions.
Zhou You
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Conventional Point-Velocity Records and Surface Velocity Observations for Estimating High Flow Discharge

open access: yesEntropy, 2014
Flow velocity measurements using point-velocity meters are normally obtained by sampling one, two or three velocity points per vertical profile. During high floods their use is inhibited due to the difficulty of sampling in lower portions of the flow ...
Giovanni Corato   +2 more
doaj   +1 more source

Comparaisons between numerical calculations and measurements in the vaned diffusor of SHF impeller [PDF]

open access: yes, 2012
The paper presents analysis of the performance and the internal flow behaviour in the vaned diffusor of a radial flow pump using PIV technique and pressure probe traverses.
ROUSSETTE, Olivier   +5 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Endwall profiling for the reduction of secondary flow in turbines [PDF]

open access: yes, 2003
This thesis describes investigations into the use of a technique for improving the efficiency of axial flow turbines. The flow in the turbine component of axial flow machines is complex, with a number of three-dimensional features.
Ingram, Grant Laidlaw, Ingram, Grant
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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