Results 101 to 110 of about 15,103,690 (309)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Pseudo Steady State Gas Flow in Tight Reservoir under Dual Mechanism Flow [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2012 Gas reservoirs with low permeability ...
Mahdi Esmailbeygi, Fariborz Rashidi
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
SDFAC:software defined flow access control mechanism
Tongxin xuebao, 2015 The software defined networking paradigm decouples control plane from data plane,offering flexible centralized control and fine grain flow management.Based on these advantages,a novel software defined access control mechanism SDFAC was proposed.Firstly ...
Xiu-lei WANG +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Flow Characteristics and Loss Mechanism of Tip Leakage Flow in Mining Contra-Rotating Axial Flow Fan
Applied SciencesTip leakage flow interacts with the mainstream, impacting the energy transmission process within the impeller of the fan and causing a significant flow loss.
Yongping Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
PriQoS:priority-differentiated flow control mechanism based on SDN
Tongxin xuebao, 2017 It was difficult to meet the increasing demand of quality of service (QoS) for the best-effort IP network,so it was urgent to develop a kind of QoS control mechanism that was compatible with the existing IP software and hardware resources.Therefore,a ...
Zhi SUN, Ming CHEN
doaj +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source