Results 161 to 170 of about 2,192,114 (314)

Flow-Through Porous Silicon Membranes for Real-Time Label-Free Biosensing

, 2016
A flow-through sensing platform based on open-ended porous silicon (PSi) microcavity membranes that are compatible with integration in on-chip sensor arrays is demonstrated.
Scott T. Retterer (1778215), Yiliang Zhao (1326870), Paul E. Laibinis (1758070), Sharon M. Weiss (1326873), Girija Gaur (2563501)   +4 more
core   +1 more source

Nash Flows Over Time with Spillback [PDF]

, 2019
Leon Sering, Laura Vargas Koch
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A comparative study of immersed-boundary interpolation methods for a flow around a stationary cylinder at low Reynolds number [PDF]

, 2013
The accuracy and computational efficiency of various interpolation methods for the implementation of non grid-confirming boundaries is assessed. The aim of the research is to select an interpolation method that is both efficient and sufficiently accurate
Wissink, J, Bahai, H, Madani, Seyed Hossein, Wissink, Jan, Madani, SH, Bahai, Hamid   +5 more
core  

Time-Resolved Characterization of Thermal and Flow Dynamics During Microchannel Flow Boiling

, 2019
The continued miniaturization and demand for improved performance of electronic devices has resulted in the need for transformative thermal management strategies.
Todd A. Kingston (6634772), Kingston, Todd A   +1 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Exploring the interactions underlying flow states: A connecting analysis of flow occurrence in European Tour golfers

, 2015
Objectives: Research to date has identified a range of factors suggested to facilitate flow states in sport. However, less attention has focused on how exactly those facilitating factors influence the occurrence of flow.
Keegan, R, Hemmings, Brian, Hemmings, B, Crust, L, Crust, Lee, Keegan, Richard, Swann, Christian, Piggott, D, Piggott, David, Swann, C   +9 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Reconstruction of Core‐Surface Flows During the Last 3,300 Years

Geochemistry, Geophysics, Geosystems
Understanding the Earth's magnetic field evolution requires examining the fluid flow at the core‐mantle boundary that drives the changes over different timescales.
Pablo Rivera, F. J. Pavón‐Carrasco, M. L. Osete   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source