Results 261 to 270 of about 2,192,114 (314)

Evaluating the additive properties of differential pressure valves in a novel benchtop shunt model. [PDF]

Fluids Barriers CNS
Chandan Reddy S, Biswas D, Maroufi SF, Williams G, Dar N, Meggyesy M, Lee RP, Suk I, Luciano M.   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Impact of temperature, humidity, dehydration, and psychological stress on salivary flow and xerostomia in young men: An observational study. [PDF]

PLoS One
Ito K, Nohno K, Funayama S, Katsura K, Kaneko N, Tanaka K, Inoue M.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Nanomembrane-based microfluidic platform with embedded electrical pressure transducer for on-chip nanoparticle quantification.

Lab Chip
Morris Z, Chawich J, Perreault O, Chewchuk S, Gragg K, Tabard-Cossa V, McGrath JL, Godin M.   +7 more
europepmc   +1 more source

Retinal arteriovenous crossings as spatiotemporal stress fields: a quantitative Doppler OCT flowmetry study. [PDF]

Sci Rep
Akiba M, Minamide K, Najac MJ, Duran LM, Haq A, Chui TYP, Rosen RB.   +6 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Reduced environmental impact in body CT imaging with deep learning reconstruction: experience of a high-volume tertiary referral center. [PDF]

Insights Imaging
Franco PN, Maino C, Gandola D, Talei Franzesi C, Corso R, De Ponti E, Ippolito D.   +6 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source