Results 101 to 110 of about 5,778,118 (308)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Two-dimensional flow of foam around an obstacle: force measurements

, 2005
A Stokes experiment for foams is proposed. It consists in a two-dimensional flow of a foam, confined between a water subphase and a top plate, around a fixed circular obstacle. We present systematic measurements of the drag exerted by the flowing foam on
Benjamin Dollet, C. Monnereau, C. S. Smith, Catherine Quilliet, Christophe Raufaste, D. R. Lide, D. Weaire, Florence Elias, François Graner, L. D. Landau, M. Lösche, Miguel Aubouy, O. H. Faxén, R. Comolet, R. G. Larson, S. J. Cox, S. J. Cox, É. Guyon   +17 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Design and Analysis of a High Force, Low Voltage and High Flow Rate Electro-Thermal Micropump

Micromachines, 2014
This paper presents the design and simulation of an improved electro-thermal micromachined pump for drug delivery applications. Thermal actuators, which are a type of Micro Electro Mechanical system (MEMS) device, are highly useful because of their ...
Ghader Yosefi, Sattar Mirzakuchaki, Farshid Raissi, Saeid Afrang   +3 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Analysis of internal flow field for a three-stage centrifugal fan under various operating conditions

The Journal of Engineering, 2018
Centrifugal fan in series is the core facility for pneumatic transportation. Its operation is required to be adjusted real time as the flow rate of transported materials changes.
Wensi Ding, Yuxun Chen, Yunke Ding
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Developing a Low-Cost Syringe Pump as a Support System for Electrospinning

Jurnal Nasional Teknik Elektro dan Teknologi Informasi
Electrospinning is one of the techniques used to fabricate nanofibers. The syringe pump is one of the main parts of electrospinning, responsible for injecting the solution into the chamber with high precision.
Dewa Pascal Ariyanto, Panji Setyo Nugroho, Della Astri Widayani, Luluk Arifatul Hikamiah, Jasmine Cupid Amaratirta, Dewanto Harjunowibowo, Yulianto Agung Rezeki   +6 more
doaj   +1 more source

Tipping Bucket Prototype for Automatic Quantification of Surface Runoff Rate in Plots

Revista Brasileira de Ciência do Solo, 2018
: Quantification of runoff rate is an onerous task with non-automated devices; it requires a lot of manual labor to perform measurements. In this study, an automatic device to quantify the surface runoff rate from plots with a small area was developed ...
André Somavilla, Paulo Ivonir Gubiani, Anderson Luiz Zwirtz   +2 more
doaj   +1 more source

Fluctuations of energy injection rate in a shear flow

, 2003
We study the instantaneous and local energy injection in a turbulent shear flow driven by volume forces. The energy injection can be both positive and negative. Extremal events are related to coherent streaks.
Aumaı̂tre, Bramwell, Bruno Eckhardt, Ciliberto, Dolowschiák, Evans, Farago, Gallavotti, Gallavotti, Goldburg, Jörg Schumacher, Lesieur, Noullez, Pinton, Rondoni, Schumacher, Schumacher, She, Titon, Vollmer   +19 more
core   +1 more source