Results 101 to 110 of about 10,091,302 (293)

Analysis of internal flow field for a three-stage centrifugal fan under various operating conditions

open access: yesThe Journal of Engineering, 2018
Centrifugal fan in series is the core facility for pneumatic transportation. Its operation is required to be adjusted real time as the flow rate of transported materials changes.
Wensi Ding, Yuxun Chen, Yunke Ding
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Application of Water-Sensitive Paper for Spray Performance Evaluation in Aeroponics via a Segmentation-Based Algorithm

open access: yesApplied Sciences
Continued population growth demands a significant increase in agricultural production to ensure food security. However, agricultural output is limited by environmental crises and the negative impacts of open-field farm practices.
Muhammad Amjad   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Design of Axial Profiling and Investigation of the Influence of Pocket Position on Lubricant Flow in Planetary Journal Bearings in Applications with Low Sliding Speeds and High Loads

open access: yesLubricants
The application of plain bearings has become very famous in planetary gear stages in recent years. To improve load-carrying capacity, this study investigates a design method for axial profiling in which a sixth-order polynomial is iteratively derived ...
Sören Henniger   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Two-phase flow meter for determining water and solids volumetric flow rate in vertical and inclined solids-in-water flows [PDF]

open access: yes
Multiphase flow can be defined as the simultaneous flow of a stream of two or more phases. Solids-in-water flow is a multiphase flows where solids and liquid are both present. Due to the density differences of the two phases, the results for such flow is
Muhamedsalih, Yousif
core   +3 more sources

Order Flow and Exchange Rate Dynamics [PDF]

open access: yes
Macroeconomic models of nominal exchange rates perform poorly. In sample, R2 statistics as high as 10 percent are rare. Out of sample, these models are typically out-forecast by a naïve random walk. This paper presents a model of a new kind.
Martin Evans and David Lyons
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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