Results 191 to 200 of about 5,778,118 (308)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The Association of Periodontal Status, Salivary Flow Rate, Salivary Cortisol Levels, and Cytokine Levels with Cognitive Status in Elderly Subjects. [PDF]

Geriatrics (Basel)
Leander MA, Karimah Z, Kuswandani SO, Lessang R, Masulili SLC, Sulijaya B, Hutomo DI, Rahdewati H, Tabeta K, Tadjoedin FM.   +9 more
europepmc   +1 more source

Restricted Flow Rate [PDF]

, 2020
openaire   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Hydrodynamic-derived centrifugal blood pump design for stable-low-flow-rate rate performance: from surface to structure. [PDF]

Bioact Mater
Jiang M, Yu C, Huang Y, Zhao X, Xu S, Zhang H, Shen Y, Han X, Chen D, Wang K, Ji X, Li M.   +11 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

The influence of hepatic arterial blood flow rate on holmium microsphere distribution: an MRI study in perfused porcine livers. [PDF]

Eur Radiol Exp
Snoeijink TJ, van den Brekel A, van der Hoek JL, Greve JGM, Remco Liefers H, Boswinkel M, Ruiter SJS, Roosen J, Jebbink EG, Nijsen JFW.   +9 more
europepmc   +1 more source

Blood Flow Rate [PDF]

, 2020
openaire   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Bayesian MCMC with Gibbs sampling for saturation flow rate estimation in heterogeneous traffic at pretimed signalized intersections. [PDF]

MethodsX
Lulusi L, Sugiarto S, Saleh SM, Isya M, Rusdi M, Rahma R.   +5 more
europepmc   +1 more source