Results 111 to 120 of about 2,404,496 (308)

A Physical Analog to Assess Surgical Face Mask Air Flow Resistance During Tidal Ventilation. [PDF]

open access: yesFront Physiol, 2022
Demoulin B   +3 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Experimental Study on Frictional Pressure Drop Characteristics of Wire-wrapped Bundles in Transition Flow

open access: yesYuanzineng kexue jishu
The investigation of frictional pressure drops in wire-wrapped bundles at low flow velocities is crucial for thermal-hydraulic studies of sodium-cooled fast reactor cores.
LI Hongrui1, , XUE Xiuli2, ZHOU Zhiwei2, ZENG Zehua1, LUO Rui1,
doaj   +1 more source

Flow diagnostics [PDF]

open access: yes, 2015
The measurement of flow properties within fluid handling systems is of utmost importance for efficient operation and control of such systems. For single phase flow systems, extensive research has been carried out world over to diagnose the flow ...
Albarzenji, Dlir   +4 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A Generalized Framework for Flow Resistance in Canopies and Granular Beds

open access: yesWater Resources Research
This study presents a generalized, theoretically grounded semi‐empirical framework for estimating flow resistance through canopies and granular beds, both of which are common in engineering and environmental applications.
Benjamin Tsai, Changhoon Lee
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Novel pinning phenomena in a superconducting film with a square lattice of artificial pinning centers

open access: yes, 2003
We study the transport properties of a superconducting Nb film with a square lattice of artificial pinning centers (APCs) as a function of dc current, at a temperature close to the superconducting transition temperature of the film.
D. A. Dikin   +5 more
core   +1 more source

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