Results 131 to 140 of about 2,404,496 (308)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Effect of Flow Resistance in Adiabatic Part on the Thermal Performance of CO₂, R134a, and R410A Two-phase Thermosyphon Loops

Zhileng xuebao
This study experimentally investigates the impact of flow resistance in risers and downcomers on the heat transfer performance of two-phase thermosyphon loops (TPTLs) with CO2, R134a, and R410A refrigerants.
Tong Zhen, Wen Xinran, Han Zekun, Fang Chunxue, Song Yulong   +4 more
doaj  

Engine Hydraulic Stability [PDF]

An analytical injector model was developed specifically to analyze combustion instability coupling between the injector hydraulics and the combustion process.
Kesselring, R. C., Sprouse, K. M.
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Optimization of the Double-sided Cooling Heatsink of IGBT Based on High Performance Turbulator

机车电传动, 2020
Based on the numerical simulation and experimental research methods, the performance of the liquid cooled radiator used in the rail transit converter was studied and optimized, and the results were compared with the current radiator used in HXD1C and ...
Guomeng SONG, Xiong WANG, Xingzhi WANG, Nan HUANG, Zhiyong WU   +4 more
doaj  

Flow boiling in rectangular microchannels: 1-D modelling of the influence of inlet resistance on flow reversal [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Gedupudi, S, Karayiannis, T, Kenning, DBR   +3 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Experimental Investigation on Pressure Drops of Purge Gas Helium in Packed Pebble Beds for Nuclear Fusion Blanket

Energies
The flow characteristics of purge gas helium in the pebble bed of the tritium breeding blanket are important in analyzing the tritium purging process and optimizing the design of the solid breeder blanket.
Hao Cheng, Baoping Gong, Bing Zhou, Juemin Yan, Long Wang, Long Zhang, Yongjin Feng, Xiaoyu Wang   +7 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Modelling of MHD Micropolar Nano Fluid Flow in an Inclined Porous Stenosed Artery with Dilatation

East European Journal of Physics
In this paper, the impact of a magnetic field on blood flow with nanofluid particles through an inclined porous stenosed artery and dilatation was studied. Here blood is treated as micropolar fluid. The equations are solved by using Homotopy perturbation
Narender Satwai, Karanamu Maruthi Prasad
doaj   +1 more source