Results 161 to 170 of about 308,255 (264)

A Responsible AI Readiness Framework for Digital Self-Management Platforms: Illustrative Application to a Rule-Based GERD Platform. [PDF]

Healthcare (Basel)
Kang SY, Lee J, Gim JA.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Intelligent DDoS Attack Detection in Software-Defined Networks Using Explainable Machine Learning. [PDF]

Sensors (Basel)
Malik JA, Naz NS, Saleem M, Khan MA.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Natural language processing for detecting endoscopy-related adverse events in free-text procedure reports at a tertiary referral centre in Türkiye: a 10-year retrospective diagnostic accuracy study. [PDF]

BMJ Open
Özden Y, Yüzügülen Ö, Büyükberber NM.   +2 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Artificial Intelligence in Respiratory Medicine: Epistemic Authority, Trust and Responsibility in Practice and in Training. [PDF]

Thorac Res Pract
Eren Akgün F, Zeynel S.
europepmc   +1 more source

A Micromechanical Study on the Flow Rule for Granular Materials

Journal of applied mechanics, 1998
WU, Jianxun, KISHINO, Yuji, ASANUMA, Hideo   +2 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Artificial intelligence-guided quantitative coronary CT assessment to rule-in or rule-out myocardial ischaemia. [PDF]

Eur Heart J Cardiovasc Imaging
Kamila PA, Nurmohamed NS, Danad I, Jukema RA, Raijmakers PG, Driessen RS, Bom MJ, van Diemen P, Pontone G, Andreini D, Chang HJ, Katz RJ, Choi AD, Knaapen P, Bax JJ, van Rosendael A, CREDENCE and PACIFIC-1 Investigators.   +16 more
europepmc   +1 more source