Results 61 to 70 of about 11,189,186 (392)

Thermal Simulation of Pipeline Flow [PDF]

SIAM Journal on Numerical Analysis, 1995
A new numerical method is presented for solving problems of one-dimensional fluid flows in pipelines with significant thermal effects. The method can be considered as a generalization to straightforward collocation. Pressure and velocity are still approximated by continuous piecewise-linear functions, but temperature is approximated with velocity ...
openaire   +2 more sources

A numerical flow simulation of a mixed flow pump [PDF]

, 2002
Mixed flow pumps are primarily axial flow pumps, but they impart some degree of radial and swirling momentum to the pump fluid as it passes through the rotor section.
Blanco, E., Fernandez, J., Parrondo, J., Scanlon, T.J., Stickland, M.T.   +4 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Simulation model of the flow in the drainage system of Ambon city withexplicit finite difference method [PDF]

, 2018
Analysis of flood modeling scenarios conducted on the simulation of urban drainage systems in Ambon city based on mathematical equations finite difference method which allows analyzing the water depth and flowing rate as a function of space and time.
Leuhery, L. (Lenora), Lewakabessy, G. (Godfried), Nara, O. D. (Obednego)   +2 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comparative analysis of water and carbon dioxide injection for the thermohydraulics of an EGS project in Dikili Geothermal Field, Türkiye

Bulletin of the Mineral Research and Exploration, 2023
A comparative numerical analysis of the thermohydraulics of an enhanced geothermal system (EGS) project in Türkiye in Dikili area is presented. The fractured granodiorite is modelled as porous media, utilizing the numerically suggested
Aydın Çiçek, Ali Cemal Benim
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Identification of elastoplastic material parameters for the solid phase of metal foams

Materials & Design
For the prediction of the mechanical behavior of foams, the effective foam properties can be calculated from the mechanical properties of the solid phase and the geometric microstructure via computer simulation.
Saeedeh Salajegheh, Hannes Grimm-Strele, Heiko Andrä   +2 more
doaj   +1 more source

Evershed and counter-Evershed flows in sunspot MHD simulations

, 2017
There have been a few reports in the literature of counter-Evershed flows observed in well developed sunspot penumbrae, i.e. flows directed towards the umbra along penumbral filaments. Here we investigate the driving forces of such counter-Evershed flows
Lagg, A., Rempel, M., Siu-Tapia, A. L., Solanki, S. K.   +3 more
core   +1 more source