Results 91 to 100 of about 488,823 (305)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Testing of powders for sensitivity to air effect segregation [PDF]

, 2011
A loss of blend homogeneity through handling operations can have a major influence on the mechanical properties of sintered products. Plant optimisation to minimise the potential for segregation of blends can be undertaken through an audit of handling ...
Berry, R.J., Bradley, M.S.A., Farnish, R.J., Guillebert, V., Kulkarni, P.   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A small scale regularly packed circulating fluidized bed. Part I: Hydrodynamics. [PDF]

, 1994
The present investigation is based on the idea of intensifying the gas¿solids contact in a circulating fluidized bed by introducing obstacles into it.
Ham, A.G.J. van der, Prins, W., Swaaij, W.P.M. van   +2 more
core   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Potential Of High-Resolution BAC-FISH In Banana Breeding [PDF]

, 2009
The genetic complexity in the genus Musa has been subject of study in many breeding programs worldwide. Parthenocarpy, female sterility, polyploidy in different cultivars and limited amount of genetic and genomic information make the production of new ...
Capdeville, G., De, Eugenio Cardamone Diniz, L., Jong, J.H.S.G.M., de, Kema, G.H.J., Souza, M.T., Swennen, R., Szinay, D., Wijnker, T.G.   +7 more
core   +2 more sources

SEBARAN ASPEK KERUANGAN TIPE LONGSORAN DI DAERAH ALIRAN SUNGAI ALO PROVINSI GORONTALO (Spread of Spatial Aspect of Landslide Types at Alo Watershed in Gorontalo Province)

Jurnal Manusia dan Lingkungan, 2015
ABSTRAK Sebaran aspek keruangan tipe longsoran di DAS Alo Provinsi Gorontalo telah dikaji dan dievaluasi menggunakan bentuk Peta Sebaran Tipe Longsoran Skala 1 : 50.000.
Fitryane Lihawa, Indriati Martha Patuti, Nurfaika Nurfaika   +2 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Application of CS100 Framework of Slide Gate Nozzle Used for 300 t Ladle

Teshugang, 2009
Process  flow  sheet  at new production area  of Masteel  is  300 t LD-LF-RH-250 mm×2150 mm  CC  line.  The INTESTOP CS 100 framework of slide gate nozzle is used for 300 t ladle, of which the maximum standard casting nozzle diameter is  100 mm ...
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doaj