Results 71 to 80 of about 488,823 (305)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Particle coating using foams and bubbles : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemical and Bioprocess Engineering at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
This thesis investigates powder coating using foams or bubbles. The work initially started on foams. Wettability studies first showed that foams can be used to coat powders. Research then focussed on the fundamental unit of foams, the bubble.
Singh, Shakti
core  

Tsunami generated by a granular collapse down a rough inclined plane

open access: yes, 2014
In this Letter, we experimentally investigate the collapse of initially dry granular media into water and the subsequent impulse waves. We systematically characterize the influence of the slope angle and the granular material on the initial amplitude of ...
Kimmoun, Olivier   +2 more
core   +3 more sources

Inferring spatial and signaling relationships between cells from single cell transcriptomic data. [PDF]

open access: yes, 2020
Single-cell RNA sequencing (scRNA-seq) provides details for individual cells; however, crucial spatial information is often lost. We present SpaOTsc, a method relying on structured optimal transport to recover spatial properties of scRNA-seq data by ...
Cang, Zixuan, Nie, Qing
core  

Numerical analysis of rapid drawdown: applications in real cases [PDF]

open access: yes, 2016
In this study, rapid drawdown scenarios were analyzed by means of numerical examples as well as modeling of real cases with in situ measurements. The aim of the study was to evaluate different approaches available for calculating pore water pressure ...
Alonso Pérez de Agreda, Eduardo   +1 more
core   +2 more sources

Experimental and numerical study of shear strength on the slide zone soil by the coupling of seepage and shear test

open access: yesScientific Reports
The stability of reservoir landslides is determined by the strength of the slide zone. Using both experimental and numerical techniques to analyze the strength of the slide zone has been widely used in the research of reservoir landslides.
Qianyun Wang   +5 more
doaj   +1 more source

Research of running contacts wear based on simulation of current distribution in the pantograph slide

open access: yesВестник Научно-исследовательского института железнодорожного транспорта, 2015
In order to solve the task related to wear reduction in the current shoe insert the authors defined the processes which have a bearing on their operation.
D. V. Tartynsky   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Microstructured Thin Film Nitinol for a Neurovascular Flow-Diverter [PDF]

open access: yes, 2016
A cerebral aneurysm occurs as a result of a weakened blood vessel, which allows blood to flow into a sac or a ballooned section. Recent advancement shows that a new device, ‘flow-diverter’, can divert blood flow away from the aneurysm sac.
Chen, Yanfei   +5 more
core   +2 more sources

Ladle Nozzle Clogging during casting of Silicon-Steel

open access: yesHigh Temperature Materials and Processes, 2019
To figure out the reason causing ladle nozzle clogging during a continuous casting process (or CC for short) for the silicon steel and get away to solve it, this paper studied the theoretical calculation of flow rates during casting, inclusions around ...
Kong Wei, Chen Ying-Feng, Cang Da-Giang
doaj   +1 more source

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