Results 61 to 70 of about 6,048,963 (333)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Experiments on seepage-triggered cliff landslides using cohesive wet sand

Progress in Earth and Planetary Science, 2022
Unsaturated wet sand possesses capillary cohesion that is lost when it becomes saturated. Thus, it can form a cliff, but a slide may be triggered upon saturation.
Fumi Shibuya, Ikuro Sumita
doaj   +1 more source

Finite element modeling of the joint action of flow slide and protective structure

Advanced Engineering Research, 2021
Introduction. In the context of the problem of plane deformation, a finite-element model of a natural landslide slope is developed. It allows for the joint work of a flow slide and a protective engineering structure.
Р. Р. Gaidzhurov, N. А. Saveleva, V. А. Dyachenkov   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

UAV and field survey investigation of a landslide triggered debris flow and dam formation in Eastern Carpathians

Frontiers in Earth Science
In the May–August period of 2010, major heavy rains impacted the Eastern Carpathians (Northeastern Romania), leading to flash floods and triggering numerous landslides.
Alin Mihu-Pintilie, Cristian Constantin Stoleriu, Andrei Urzică, Andrei Urzică   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Letter from the Editor

, 2012
In the act of pondering the majesty of God’s Creation, I never tire of observing the slide of Autumn as it nestles into Winter and the beauty of the snow that follows.
Belcher, E. Christina
core   +1 more source

Research of running contacts wear based on simulation of current distribution in the pantograph slide

Вестник Научно-исследовательского института железнодорожного транспорта, 2015
In order to solve the task related to wear reduction in the current shoe insert the authors defined the processes which have a bearing on their operation.
D. V. Tartynsky, M. N. Yemelyanova, A. T. Tibilov   +2 more
doaj   +1 more source

Holographic Wilsonian RG flow and sliding membrane paradigm [PDF]

Journal of High Energy Physics, 2011
21pages, 9 figures, published version, minor ...
Sin, Sang-Jin, Zhou, Yang
openaire   +2 more sources

Launching to the Moon and Beyond: Ares I and V Updates [PDF]

, 2008
This slide presentation reviews the progress made on the Ares I and Ares V launch vehicles. Slides reviewing NASA's Mission, timetable and the Launch Vehicle comparisons between the shuttle and the Saturn V vehicles and the Ares I and V launch vehicles ...
Davis, Daniel J.
core   +1 more source