Microstructure and compressive flow stress of directionally solidified ternary Ni3(Al, Nb) and quaternary Ni3(Al, Nb, Ti) alloys with duplexphase [PDF]
Koji Hagihara +2 more
openalex +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Recurrent Neural Network (RNN)-Based Approach to Predict Mean Flow Stress in Industrial Rolling
This study addresses the usage of data from industrial plate mills to calculate the mean flow stress of different steel grades. Accurate flow stress values may optimize rolling technology, but the existing literature often provides coefficients like ...
Alexey G. Zinyagin +5 more
doaj +1 more source
An Alzheimer's Disease Mechanism Based on Early Pathology, Anatomy, Vascular-Induced Flow, and Migration of Maximum Flow Stress Energy Location with Increasing Vascular Disease. [PDF]
Trumbore CN, Raghunandan A.
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Prediction of Flow Stress of Annealed 7075 Al Alloy in Hot Deformation Using Strain-Compensated Arrhenius and Neural Network Models. [PDF]
Yang H, Bu H, Li M, Lu X.
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Random Forest Approach in Modeling the Flow Stress of 304 Stainless Steel during Deformation at 700 °C-900 °C. [PDF]
Song SH.
europepmc +1 more source
Analysis of the Reynolds stress tensor for unsteady flows in URANS models
Mauro Grioni +3 more
openalex +1 more source

