Results 31 to 40 of about 299,906 (268)

Mesoscopic seepage velocity characteristics during heap leaching based on magnetic resonance imaging

open access: yes工程科学学报, 2015
Column leaching seepage processes were detected in a non-contact and non-destructive way by magnetic resonance imaging. Column leaching images were obtained when the flow was stationary and running.
YIN Sheng-hua   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

SWIRL FLOW ANALYSIS BASED ON ELECTRICAL CAPACITANCE TOMOGRAPHY

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2016
This paper describes an application of dual-plane Electrical Capacitance Tomography (ECT) system for gas-solid swirl flow measuremetns. The angular component of the velocity in the pipes cross section was calculated.
Ayoub Saoud   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Increased macular choroidal blood flow velocity during systemic corticosteroid therapy in a patient with acute macular neuroretinopathy

open access: yesClinical Ophthalmology, 2012
Yuki Hashimoto,1 Wataru Saito,1,2 Shohei Mori,1 Michiyuki Saito,1 Susumu Ishida1,21Department of Ophthalmology, 2Department of Ocular Circulation and Metabolism, Hokkaido University Graduate School of Medicine, Sapporo, JapanPurpose: The precise ...
Hashimoto Y   +4 more
doaj  

Experimental Investigation of the Effect of Hydraulic Jump Location on Flow Velocity in Type II Stilling Basin [PDF]

open access: yesعلوم و مهندسی آبیاری, 2014
Hydraulic condition of stilling basin, in particular, the flow rate passing through chute spillway, as well as the location of hydraulic jump plays an important role on velocity fluctuations in a stilling basin.
Manouchehr Fathi Moghadam, Ehsan Parsi
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Effect of Flow Velocity on Laminar Flow in Microfluidic Chips

open access: yesMicromachines, 2023
Gel fibers prepared based on microfluidic laminar flow technology have important research value in constructing biomimetic scaffolds and tissue engineering. The key point of microfluidic laminar flow technology is to find the appropriate fluid flow rate in the micropipe. In order to explore the influence of flow rate on the laminar flow phenomenon of a
Chuang Wu   +3 more
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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