Results 51 to 60 of about 7,809,143 (340)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SWIRL FLOW ANALYSIS BASED ON ELECTRICAL CAPACITANCE TOMOGRAPHY

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2016
This paper describes an application of dual-plane Electrical Capacitance Tomography (ECT) system for gas-solid swirl flow measuremetns. The angular component of the velocity in the pipes cross section was calculated.
Ayoub Saoud   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experimental Investigation of the Effect of Hydraulic Jump Location on Flow Velocity in Type II Stilling Basin [PDF]

open access: yesعلوم و مهندسی آبیاری, 2014
Hydraulic condition of stilling basin, in particular, the flow rate passing through chute spillway, as well as the location of hydraulic jump plays an important role on velocity fluctuations in a stilling basin.
Manouchehr Fathi Moghadam, Ehsan Parsi
doaj  

Pressure and velocity measurements in a three-dimensional wall jet [PDF]

open access: yes, 1978
The effects on the flow fields of varying the ratio of the velocity at the exit plane of the nozzle to the outer tunnel flow are reported. The pressure-velocity correlations are taken and some trends are discussed.
Catalano, G. D.   +2 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Increased macular choroidal blood flow velocity during systemic corticosteroid therapy in a patient with acute macular neuroretinopathy

open access: yesClinical Ophthalmology, 2012
Yuki Hashimoto,1 Wataru Saito,1,2 Shohei Mori,1 Michiyuki Saito,1 Susumu Ishida1,21Department of Ophthalmology, 2Department of Ocular Circulation and Metabolism, Hokkaido University Graduate School of Medicine, Sapporo, JapanPurpose: The precise ...
Hashimoto Y   +4 more
doaj  

Slow-light pulses in moving media

open access: yes, 2002
Slow light in moving media reaches a paradoxical regime when the flow speed of the medium approaches the group velocity of light. Pulses can penetrate a region where a counter-propagating flow exceeds the group velocity.
Fiurasek, J.   +2 more
core   +1 more source

A Raman anemometer for component-selective velocity measurements of particles in a flow [PDF]

open access: yes, 1981
An anemometer for the measurement of the velocity of particles of different components in a flow, separate and apart from that of the flow itself, is described. As a component-selective mechanism Raman scattering is used.
Florisson, O.   +2 more
core   +2 more sources

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