Results 61 to 70 of about 7,809,143 (340)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The impact of water flow rate on the dynamic dissolution kinetics of fractured limestone formations

Frontiers in Earth Science
To break through the lithological constraints on the surrounding rock for the construction of underground water-sealed oil storage caverns, and considering limestone as a potential host rock for such caverns, the dynamic evolution law of fracture ...
Dabao Xu, Yuhang Ma, Bo Feng, Mingming Fan, Zhenchuan Han   +4 more
doaj   +1 more source

Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography.

Biomedical Optics Express, 2013
The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was recently developed as a method for imaging blood flow in the human retina without the use of phase information.
J. Tokayer, Yali Jia, Al-Hafeez Z. Dhalla, David Huang   +3 more
semanticscholar   +1 more source

Prediction of aerodynamic flow fields using convolutional neural networks [PDF]

Computational Mechanics, 2019
An approximation model based on convolutional neural networks (CNNs) is proposed for flow field predictions. The CNN is used to predict the velocity and pressure field in unseen flow conditions and geometries given the pixelated shape of the object.
Yaser Afshar, Saakaar Bhatnagar, Shaowu Pan, K. Duraisamy, S. Kaushik   +4 more
semanticscholar   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Force-velocity correlations in a dense, collisional, granular flow [PDF]

, 2005
We report measurements in a 2-dimensional, gravity-driven, collisional, granular flow of the normal force delivered to the wall and of particle velocity at several points in the flow. The wall force and the flow velocity are negatively correlated.
Dragulin, Sonia, Easwar, Nalini, Gardel, Emily, Keene, Ellen, Menon, Narayanan   +4 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Aerodynamic Characteristics of High-speed Train Pantographs Based on Jet Flow Control [PDF]

Journal of Applied Fluid Mechanics
The pantograph is a critical instrument that significantly affects the aerodynamics of high-speed trains, posing a considerable challenge to the energy conservation and environmental protection of trains.
S. Huang, B. D. Zhang, Z. W. Li, J. P. Zhao, W. J. Peng, J. R. Lin   +5 more
doaj   +1 more source

An approach of flow velocity measurement on microfluidic chip by near-field scanning microwave microscopy

AIP Advances, 2023
A novel approach for flow velocity measurements on a microfluidic chip using near-field scanning microwave microscopy (NSMM) is proposed. It does not require the tested sample to contain visible particles, as the intrinsic electromagnetic properties of ...
Zhiwei Yuan, Han Luo, Yujie Chen, Xiangyue Yang, Yue Wu, Zhe Wu, Jianlong Liu, Yubin Gong, Baoqing Zeng   +8 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source