Results 101 to 110 of about 4,348,404 (302)

Reliable Validation Based on Optical Flow Visualization for CFD Simulations

open access: yes, 2003
A reliable validation based on the optical flow visualization for numerical simulations of complex flowfields is addressed in this paper. Several test cases, including two-dimensional, axisymmetric and three-dimensional flowfields, were presented to ...
姜宗林
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Visualization of Flow Field: Application of PLIF Technique

open access: yesJournal of Spectroscopy, 2018
The objective of this paper is to apply planar laser-induced fluorescence (PLIF) technology to flow field visualization. This experiment was carried out in a one-meter wind tunnel to study the wake flow field around a circular cylinder.
Jiang Bo Peng   +10 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Effect of Oil on Flow Boiling Heat Transfer and Flow Patterns of CO2 in 11.2 mm Horizontal Smooth and Enhanced Tube [PDF]

open access: yes, 2012
Flow boiling heat transfer characteristics of CO2 with and without oil were investigated experimentally in horizontal smooth and enhanced tubes with an inner diameter of 11.2 mm.
Hrnjak, Predrag S., Kim, Seongho
core  

Flow Visualisation by Condensing Steam – an Unusual Method Applied to Development of a Low Reynolds Number Fluidic Selector Valve

open access: yesActa Polytechnica, 2005
A visualization method so far not mentioned in the literature has been recently developed by the authors as a useful validation supplement to numerical flowfield computations in the design of microfluidic devices.
J. R. Tippetts, V. Tesař
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Unsteady Aerodynamics of Delta Kites for Airborne Wind Energy Under Dynamic Stall Conditions

open access: yesWind Energy
Three unsteady aerodynamic tools at different levels of fidelity and computational cost were used to investigate the unsteady aerodynamic behavior of a delta kite applied to airborne wind energy.
I. Castro‐Fernández   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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