Results 121 to 130 of about 1,249,001 (308)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Vortex flow hysteresis [PDF]

open access: yes
An experimental study was conducted to quantify the hysteresis associated with various vortex flow transition points and to determine the effect of planform geometry.
Cunningham, A. M., Jr.
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Advanced designs for fluid flow visualization [PDF]

open access: yes
Research was carried out on existing and new designs for minimally intrusive measurement of flow fields in the Geophysical Fluid Flow Cell and the proposed Atmospheric General Circulation Experiment. The following topics are discussed: (1) identification

core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

In-flight flow visualization results from the X-29A aircraft at high angles of attack [PDF]

open access: yes
Flow visualization techniques were used on the X-29A aircraft at high angles of attack to study the vortical flow off the forebody and the surface flow on the wing and tail.
Delfrate, John H., Saltzman, John A.
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

FlowLLM: Large language model driven flow visualization

open access: yesVisual Informatics
Flow visualization is an essential tool for domain experts to understand and analyze flow fields intuitively. In the past decades, various interactive techniques were developed to customize flow visualization for exploration.
Zilin Li, Weihan Zhang, Jun Tao
doaj   +1 more source

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