Results 141 to 150 of about 4,348,404 (302)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

FlowLLM: Large language model driven flow visualization

open access: yesVisual Informatics
Flow visualization is an essential tool for domain experts to understand and analyze flow fields intuitively. In the past decades, various interactive techniques were developed to customize flow visualization for exploration.
Zilin Li, Weihan Zhang, Jun Tao
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Optical flow visualization

open access: yes, 2010
Optical flow visualization techniques rely on the changes in flow density and hence the refractive index of the flow. Through various flow visualization techniques an image of the flow field is obtained which can be either qualitative, quantitative, or ...
Kontis, K.   +5 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Holographic flow visualization: State-of-the-art overview [PDF]

open access: yes, 1982
Components and system designs of holographic flow visualization techniques are reviewed.
Trolinger, J. D.
core  

Research on Big Data Visualization Methods of Urban Rail Transit Passenger Flow

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveThe existing static chart analysis methods fail to intuitively demonstrate the time-variability of passenger flow data with time or the spatial asymmetry varying with spatial attributes.
Zheng JIANG, Xikui LYU, Xinhua LIU
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

3D Printed Biomodels for Flow Visualization in Stenotic Vessels: An Experimental and Numerical Study. [PDF]

open access: yesMicromachines (Basel), 2020
Carvalho V   +5 more
europepmc   +1 more source

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