Results 131 to 140 of about 4,348,404 (302)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Synchronized resistive-pulse analysis with flow visualization for single micro- and nanoscale objects driven by optical vortex in double orifice. [PDF]

Sci Rep, 2021
Nakajima K, Nakatsuka R, Tsuji T, Doi K, Kawano S.   +4 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Abstract Design and Implementation of Geometric and Texture-Based Flow

, 2008
Usually, research related software consists of individual, isolated prototypes because researchers are interested in a small proof-ofconcept application for demonstration.
Visualization Techniques
core  

Quantitative flow visualization of a turboprop aircraft by robotic volumetric velocimetry

, 2018
The flow field around a turboprop aircraft scaled model is investigated with attention to the propeller slipstream and the wing near wake. The experiments are conducted in the Low-Speed Tunnel (LST) of the German-Dutch Wind Tunnels (DNW) as part of a ...
Schneiders, J.F.G. (author), Sciacchitano, A., Giaquinta, D., Giaquinta, Daniele (author), Schneiders, J.F.G., van Rooijen, B.D., Funes, D.E., Sciacchitano, A. (author), Funes, D.E. (author), van Rooijen, B.D. (author), Scarano, F. (author), Scarano, F.   +11 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Live Intravital Intestine with Blood Flow Visualization in Neonatal Mice Using Two-photon Laser Scanning Microscopy. [PDF]

Bio Protoc, 2021
Koike Y, Li B, Chen Y, Ganji N, Alganabi M, Miyake H, Lee C, Hock A, Wu R, Uchida K, Inoue M, Delgado-Olguin P, Pierro A.   +12 more
europepmc   +1 more source

Flowing with the visual stream [PDF]

Nature Reviews Neuroscience, 2019
openaire   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Software Aids Visualization of Computed Unsteady Flow [PDF]

, 2003
Unsteady Flow Analysis Toolkit (UFAT) is a computer program that synthesizes motions of time-dependent flows represented by very large sets of data generated in computational fluid dynamics simulations.
Kenwright, David, Kao, David
core