Results 71 to 80 of about 596,194 (249)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Spreading Kinetics of Herschel-Bulkley Fluids Over Solid Substrates

Frontiers in Physics, 2020
The spreading kinetics of Herschel-Bulkley fluids on horizontal solid substrates were theoretically studied. The equations of film thickness were derived in both gravitational and capillary regimes.
Jie Zhang, Jie Zhang, Hai Gu, Hai Gu, Jianhua Sun, Bin Li, Bin Li, Jie Jiang, Jie Jiang, Weiwei Wu   +9 more
doaj   +1 more source

Development of Eco-Friendly Ramp Control for Connected and Automated Electric Vehicles [PDF]

, 2020
With on-board sensors such as camera, radar, and Lidar, connected and automated vehicles (CAVs) can sense the surrounding environment and be driven autonomously and safely by themselves without colliding into other objects on the road. CAVs are also able
Barth, Matthew J., Wang, Ziran, Wu, Guoyuan, Zhao, Zhouqiao   +3 more
core  

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Synthetic X-ray light curves of BL Lacs from relativistic hydrodynamic simulations

, 2004
We present the results of relativistic hydrodynamic simulations of the collision of two dense shells in a uniform external medium, as envisaged in the internal shock model for BL Lac jets.
Aloy, Bednarz, Bednarz, Bicknell, Brinkmann, Brinkmann, Bykov, Colella, Daigne, E. Müller, Edelson, Fossati, Jones, Kardashev, Kataoka, Kataoka, M. A. Aloy, Malizia, Maraschi, Martí, Mastichiadis, Miniati, Moderski, P. Mimica, Pian, Sikora, Spada, Takahashi, Takahashi, Takahashi, Tanihata, Urry, W. Brinkmann, Zhang   +33 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Steady Flow of Purely Viscous Shear-Thinning Fluids in a 1:3 Planar Gradual Expansion

Journal of Applied Fluid Mechanics, 2019
Laminar flow of non-Newtonian fluid (shear-thinning) through a 1:3 planar gradual expansion is numerically investigated, for various Power-Law index (0.6, 0.8 and 1.0) and expansion angles (15, 30, 45, 60 and 90°) at different generalized Reynolds number
A. Menouer, N. Sad Chemloul, K. Chaib, A. Kadari   +3 more
doaj  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Application of Seismic Attribute Technique to estimate the 3D model of Hydraulic Flow Units: A case study of a gas field in Iran

Egyptian Journal of Petroleum, 2018
One of the most important steps in evaluation and development of hydrocarbon reservoirs is the mapping of their characteristics. Nowadays, Seismic Attribute Technique is used to build parameters of hydrocarbon reservoirs in inter-well spaces.
Mohamad Iravani, Mahdi Rastegarnia, Dariush Javani, Ali Sanati, Seyed Hasan Hajiabadi   +4 more
doaj   +1 more source