Results 71 to 80 of about 257,657 (314)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Phenological scale for the mortiño or agraz (Vaccinium meridionale Swartz) in the high Colombian Andean area

open access: yesRevista Facultad Nacional de Agronomía Medellín, 2019
Mortiño, Vaccinium meridionale Swartz, represents a viable alternative for fruit growing because of the presence of appropriate ecological niches and spontaneous populations in the Colombian Andean zone.
Clara I. Medina Cano   +2 more
doaj   +1 more source

In vitro flowering red miniature rose

open access: yes, 2013
Using aseptic plantlets obtained from stem node explants of hybrid red miniature rose (Rosa hybrida cv. Fairy Dance), the effects of shoot physiological status, medium ingredients, and culture thermoperiod on in vitro flowering were evaluated.
J. A. Teixeira da Silva   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Diversidad y distribución del género Salvia (Lamiaceae) en Michoacán, México Diversity and distribution of the genus Salvia (Lamiaceae) in Michoacan, Mexico

open access: yesRevista Mexicana de Biodiversidad, 2011
Se presenta la riqueza y distribución de las especies de Salvia en los municipios del estado de Michoacán con datos florísticos y ecológicos para cada especie. Con base en trabajo de campo y revisión de ejemplares depositados en los herbarios CIMI, EBUM,
Guadalupe Cornejo-Tenorio   +1 more
doaj  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Floral visitors and reproductive success in two sequentially flowering Lindera shrubs (Lauraceae) of central Japan [PDF]

open access: yes, 2019
Two Lindera species (Lindera praecox and Lindera triloba) are distributed sympatrically along the Pacific Ocean side of the main island of Japan. They are similar, but not identical, in habitat preference and flowering season. Slight differences in these
Matsushita, Michinari   +5 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Flowers and Flower Lore

open access: yesThe American Journal of Psychology, 1888
Mode of access: Internet. ; OSU's copy 1 gift of Ann W. and Emanual D. Rudolph.
openaire   +1 more source

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