Results 71 to 80 of about 99,394 (285)

Transcription Factor SOX5 Promotes the Migration and Invasion of Fibroblast-Like Synoviocytes in Part by Regulating MMP-9 Expression in Collagen-Induced Arthritis

Frontiers in Immunology, 2018
ObjectivesFibroblast-like synoviocytes (FLS) exhibit a unique aggressive phenotype in rheumatoid arthritis (RA). Increased FLS migration and subsequent invasion of the extracellular matrix are essential to joint destruction in RA.
Yumeng Shi, Qin Wu, Wenhua Xuan, Xiaoke Feng, Fang Wang, Betty P. Tsao, Miaojia Zhang, Wenfeng Tan   +7 more
doaj   +1 more source

On the melting of the nanocrystalline vortex matter in high-temperature superconductors

, 2005
Multilevel Monte Carlo simulations of the vortex matter in the highly-anisotropic high-temperature superconductor Bi$_2$Sr$_2$CaCu$_2$O$_8$ were performed. We introduced low concentration of columnar defects satisfying $B_\phi\le B$.
Eduardo Cuansing, G. S. Mkrtchyan, G. W. Crabtree, Yadin Y. Goldschmidt   +3 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Average Infrared Galaxy Spectra From Spitzer Flux Limited Samples

, 2008
The mid-infrared spectroscopic analysis of a flux-limited sample of galaxies with fv(24um) > 10 mJy is presented. Sources observed are taken from the Spitzer First Look Survey (FLS) catalog and from the NOAO Deep Wide-Field Survey region in Bootes (NDWFS)
Brandl, Brown, Calzetti, Caputi, Chary, Cool, Daniel W. Weedman, Desai, Fadda, Farrah, Gunn, Hao, Ho, Houck, Houck, James R. Houck, Jannuzi, Lagache, Le Floc'h, Papovich, Pope, Rieke, Spoon, Weedman, Yan   +24 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Acylcarnitine enrichment as a characteristic of rheumatoid arthritis fibroblast-like synoviocyte metabolic fingerprint

Journal of Translational Autoimmunity
Objective: In rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLS) alter their metabolism to support their activation. We aimed to analyse the full spectrum of metabolic alterations associated with RA by performing untargeted metabolomics in RA ...
Georgios K. Vasileiadis, Yuan Zhang, Marion Laudette, Tahzeeb Fatima, Anna-Karin Hultgård Ekwall, Reshmi Sureshkumar, Ronald van Vollenhoven, Jon Lampa, Bjorn Gudbjornsson, Espen A. Haavardsholm, Dan Nordström, Gerdur Gröndal, Kim Hørslev-Petersen, Kristina Lend, Merete L. Hetland, Michael Nurmohamed, Mikkel Østergaard, Till Uhlig, Tuulikki Sokka-Isler, Anna Rudin, Jan Borén, Monica Guma, Cristina Maglio   +22 more
doaj   +1 more source

Hypoxia-induced miR-191-C/EBPβ signaling regulates cell proliferation and apoptosis of fibroblast-like synoviocytes from patients with rheumatoid arthritis

Arthritis Research & Therapy, 2019
Background Hypoxia plays an important role in the proliferation of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS), leading to pathology of RA.
Shanshan Yu, Ying Lu, Ming Zong, Qi Tan, Lieying Fan   +4 more
doaj   +1 more source

Melting of Flux Lines in an Alternating Parallel Current

, 1998
We use a Langevin equation to examine the dynamics and fluctuations of a flux line (FL) in the presence of an {\it alternating longitudinal current} $J_{\parallel}(\omega)$.
A. E. Koshelev, A. I. Larkin, B. Khaykovich, D. Ertas, D. Ertas, D. Ertas, D. Ertas, D. R. Nelson, D. R. Nelson, D. R. Nelson, D. S. Fisher, E. H. Brandt, E. H. Brandt, E. H. Brandt, E. H. Brandt, G. Blatter, G. D’Anna, G. D’Anna, I. S. Aranson, J. Bardeen, L. Radzihovsky, L. Tang, M. P. A. Fisher, M. P. A. Fisher, M. V. Feigel’man, M. Wallin, Mehran Kardar, Mohammad Kohandel, R. K. P. Zia, R. Kamien, T. Giamarchi, T. Giamarchi, T. Giamarchi, W. Krauth, W. S. Seow, Y. Y. Goldschmidt   +35 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

The Spitzer Space Telescope First-Look Survey: Neutral Hydrogen Emission

, 2005
The Spitzer Space Telescope (formerly SIRTF) extragalactic First-Look Survey covered about 5 square degrees centered on J2000 17:18 +59:30 in order to characterize the infrared sky with high sensitivity.
Boulanger F., Deul E., Felix J. Lockman, Herbstmeier U., J. J. Condon, Kalberla P., Kalberla P., Lagache G., Lagache G., Liszt H., Penprase B., Wakker B., Wakker B., Williams D.   +13 more
core   +1 more source