Results 61 to 70 of about 47,013 (254)
Flu-like pandemics and metaphor pre-covid: A corpus investigation
, 2021 The use of metaphor in framing COVID-19 has already attracted considerable attention in both academic and public debate and we have seen extensive discussion of how this pandemic might be compared to past events, such as the so-called ‘Spanish flu’ of ...
Charlotte Taylor (4464820) +3 more
core +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FLU-PRO domain and total score descriptive statistics Day 1.
, 2018 FLU-PRO domain and total score descriptive statistics Day 1.
Andrea Dugas (4993790) +29 more
core +1 more source
, 2023 <h3>Fixes</h3> <ul> <li>docs updated to show proper profile to run test profiles for Illumina and Nanopore locally (#52)</li> <li><code>test_nanopore</code> profile has been updated to run locally with < ...
Kruczkiewicz, Peter +2 more
core +1 more source
Клинико-эпидемиологическая характеристика гриппа в постпандемический период [PDF]
Саратовский научно-медицинский журнал, 2013 Objective: To analyze the clinical and epidemiological characteristics in the post-pandemic influenza seasons in 2010/11/12/13 years. Material and methods: The analysis of the incidence of acute respiratory viral infections and flu in the Saratov region ...
Maleev V.V. +6 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
An influenza pandemic : what it could mean for Scottish tourism [PDF]
, 2006 There is a growing unease among World Health Organisation (WHO) officials and other global disease surveillance organisations that Avian Flu will mutate into a human influenza pandemic.
Page, Stephen +4 more
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MedicinaBackground and Objectives: Acute infections among elite athletes are predominantly attributed to upper respiratory tract pathogens. From a practical standpoint, medical personnel responsible for the healthcare of professional football players should be ...
Dimitrios Papagiannis +6 more
doaj +1 more source