A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Who Takes Advantage of Free Flu Shots? Examining the Effects of an Expansion in Coverage [PDF]
Because of the high risk of costly complications (including death) and the externalities of contagious diseases, many countries provide free flu shots to certain populations free of charge.
Carman, K.G., Mosca, I.
core +1 more source
Representations of swine flu: Perspectives from a Malaysian pig farm [PDF]
© The Author(s), 2010. This is the author's accepted manuscript. The final published article is available from the link below.Novel influenza viruses are seen, internationally, as posing considerable health challenges, but public responses to such ...
Dhanoa, A +3 more
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
What Are Americans' Most Pressing Health Concerns? [PDF]
Summarizes findings from a June 2006 survey on health issues Americans are most concerned about, such as developing heart disease, diabetes, obesity-related illnesses, and avian flu.
Chioma Uzoigwe
core
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality. [PDF]
The worldwide spread of a novel influenza A (H1N1) virus in 2009 showed that influenza remains a significant health threat, even for individuals in the prime of life.
Bourbeau, Robert +6 more
core +2 more sources
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Who can stay home with the flu? [PDF]
As fears of a swine flu pandemic spread, President Obama and public health officials are urging Americans to stay home from work and keep their children home from school if they have flu symptoms.
Marilyn P. Watkins
core
PocketCare: Tracking the Flu with Mobile Phones using Partial Observations of Proximity and Symptoms
Mobile phones provide a powerful sensing platform that researchers may adopt to understand proximity interactions among people and the diffusion, through these interactions, of diseases, behaviors, and opinions.
Dong, Wen +3 more
core +1 more source

