Results 141 to 150 of about 106,245 (320)

Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates

open access: yesBrazilian Journal of Infectious Diseases, 2016
The antifungal activity of tacrolimus in combination with antifungal agents against different fungal species has been previously reported. Here we report the in vitro interactions between tacrolimus and amphotericin B, fluconazole, itraconazole, and ...
Thaís Felli Kubiça   +6 more
doaj  

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

open access: yes, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina   +3 more
core  

A Prospective Surveillance Study of Candidaemia : Epidemiology, Risk Factors, Antifungal Treatment and Outcome in Hospitalized Patients [PDF]

open access: yes, 2016
Funding This work was supported by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/Z. Data collection was supported by a grant from Pfizer.
Deshpande, Ashutosh   +8 more
core   +2 more sources

Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose

open access: yesAdvanced Materials, Volume 37, Issue 22, June 5, 2025.
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew   +2 more
wiley   +1 more source

Expert Consensus on the Clinical Application of PI3K/AKT/mTOR Inhibitors in the Treatment of Breast Cancer (2025 Edition)

open access: yesCancer Innovation, Volume 4, Issue 3, June 2025.
ABSTRACT Background The phosphoinositide 3‐kinase (PI3K)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway (PAM pathway) plays a critical role in breast cancer pathogenesis and progression, and is closely linked with resistance to endocrine therapy in advanced breast cancer.
The Breast Cancer Expert Committee of the National Quality Control Center for Cancer   +3 more
wiley   +1 more source

A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole

open access: yesPLoS Biology, 2014
When exposed to the antifungal drug fluconazole, Candida albicans undergoes abnormal growth, forming three-lobed “trimeras.” These aneuploid trimeras turn out genetically variable progeny with varying numbers of chromosomes, increasing the odds of ...
Benjamin D. Harrison   +8 more
semanticscholar   +1 more source

Outcomes With Venetoclax 50 mg, Hypomethylating Agents, and Voriconazole or Posaconazole in Acute Myeloid Leukemia

open access: yeseJHaem, Volume 6, Issue 3, June 2025.
ABSTRACT Background Real‐world evidence for hypomethylating agent (HMA) + venetoclax 50 mg (VEN50) with voriconazole and posaconazole in acute myeloid leukemia (AML), is limited. Methods We evaluated outcomes of patients with newly‐diagnosed AML treated with HMA + VEN50 with either posaconazole (n = 23) or voriconazole (n = 95).
Kendall Diebold   +9 more
wiley   +1 more source

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