Results 141 to 150 of about 87,404 (254)

Polygonum cognatum Extract: Multitarget Anti‐inflammatory, Antidiabetic, and Epigenetic Modulation Properties

ChemistryOpen, Volume 15, Issue 2, February 2026.
Polygonum cognatum extracts exhibit strong antioxidant, anti‐inflammatory, antidiabetic, and antimicrobial activities. This study demonstrates, for the first time, histone deacetylase inhibitory activity, revealing epigenetic modulation potential.
Serhat Karaman, Yakup Budak, Elif Aktürk Bozdemir   +2 more
wiley   +1 more source

Lipase Gene Expression of Resistant and Sensitive Candida Albicans to Fluconazole Isolated from Patients Suffering from Oral Candidiasis and Vaginal Candidiasis

Medical Laboratory Journal, 2015
Background and Objective: With the development of drug resistance in strains of fungi, there is a considerable resistance of Candida albicans strains to fluconazole. Molecular studies are developing to determine the relationship of such a drug resistance
Nasrollahi Omran, A, Nazemi, A, Kihanian, SH, Aryana , N   +3 more
doaj  

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]

, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho, Hamed I. Ali, Hukihisa Fujita, Morio Yamada   +3 more
core   +1 more source

Pulmonary Tropheryma whipplei Infection Presenting With Multiple Thick‐Walled Cavities on Chest CT: A Case Report and Literature Review

Respirology Case Reports, Volume 14, Issue 2, February 2026.
This case report highlights a rare instance of pulmonary infection caused by Tropheryma whipplei, presenting with distinctive imaging features on chest CT: multiple round or oval thick‐walled consolidations with small central cavities (approximately 1 mm in diameter) and subpleural distribution.
Yang Liu, Handan Fu
wiley   +1 more source

Hyalohyphomycotic chronic rhinosinusitis caused by Microascus cirrosus in a cat

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 13‐year‐old, male, neutered, indoor‐only, domestic long‐haired cat was presented with an 8‐month history of sneezing and a 2‐month history of epistaxis. Computed tomography demonstrated an irregular contrast‐enhancing soft tissue opacity within both nasal cavities and osteolysis of surrounding bony structures.
Leonel Frutuoso, Samuel Fowlie, Sean Haugland, Emma Corbett, Christopher Scudder   +4 more
wiley   +1 more source

Fluconazole-resistant oral candidosis in a repeatedly treated female AIDS patient. [PDF]

, 1994
Anonymous, British Society for Antimicrobial Chemotherapy Working Party, Fan-Havard, Fox, Galgiani, Johnson, Kitchen, Korting, Korting, Korting, Laine, McCarthy, Ollert, Rogers, Samaranayake, Smith, Warnock, Willocks, Wit   +18 more
core   +1 more source

Variation in fluconazole efficacy for Candida albicans strains sequentially isolated from oral cavities of patients with AIDS in an experimental murine candidiasis model [PDF]

, 1996
Francesco Barchiesi, Laura K. Najvar, Michael Luther, Giorgio Scalise, Michael G. Rinaldi, John R. Graybill   +5 more
openalex   +1 more source

Efavirenz and CYP2C9 Genetic Polymorphisms Reduce CYP2C9 Activity in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Efavirenz's effects on cytochrome P450 2C9 (CYP2C9) activity have not been formally characterized in vivo. We conducted the first clinical drug–drug interaction (DDI) study to test the effect of chronic efavirenz dosing on CYP2C9 activity, using tolbutamide as a selective probe.
Jason D. Kim, Ingrid F. Metzger, Jessica Bo Li Lu, Todd C. Skaar, Zeruesenay Desta   +4 more
wiley   +1 more source

One‐year usage patterns of SGLT‐2 inhibitors and GLP‐1 receptor agonists in individuals with type 2 diabetes in a real‐world population

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 972-981, February 2026.
Abstract Aims Real‐world studies of sodium‐glucose co‐transporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) typically assess adherence and discontinuation as separate outcomes. We applied a novel approach that integrates these measures to categorize patterns of drug usage.
Louise A. Donnelly, Katyayeni Singh, Rory J. McCrimmon, Ewan R. Pearson   +3 more
wiley   +1 more source

Emergence of Candida (Candidozyma) auris in Minas Gerais, Brazil: Genomic Surveillance to Guide Rapid Public Health Responses

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé, Dhian Renato Almeida Camargo, Rafael Wesley Bastos, Sara Cândida Ferreira dos Santos, Natália Rocha Guimarães, Sílvia Helena Sousa Pietra Pedroso, Paulo Eduardo de Souza da Silva, Aristóteles Góes‐Neto, Lida Jouca de Assis Figueredo, Gabriella da Côrte Castro, Ana Maria Ribeiro Nunes Rodrigues, Flavia Ribeiro Soares Cruzeiro, Nádia Aparecida Campos Dutra, Josiane Barbosa Piedade Moura, Glauco de Carvalho Pereira, Carmem Dolores Faria, Marta Giovanetti, Felipe Campos de Melo Iani, Luiz Carlos Júnior Alcantara, Talita Émile Ribeiro Adelino   +19 more
wiley   +1 more source