Results 151 to 160 of about 48,304 (212)

Saliva Based Clozapine Therapeutic Drug Monitoring: A Systematic Review

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT Clozapine is superior in the treatment of treatment‐refractory schizophrenia but requires therapeutic drug monitoring (TDM) due to its unpredictable pharmacokinetics and dose‐dependent side effects. This systematic review evaluates saliva as a more patient‐friendly sampling strategy for clozapine TDM.
Tessa Rademaker, Rachel Chu, Suhaila Hasan, Anthony Harris, Jan‐Willem Alffenaar   +4 more
wiley   +1 more source

Antifungal efficacy of cinnamaldehyde and nano-cinnamaldehyde particles against candidiasis: an in-vitro study. [PDF]

BMC Oral Health
Molania T, Saeedi M, Morteza-Semnani K, Negarandeh R, Hosseinnataj A, Lotfizadeh A, Fadaei H, Jafari A, Salehi M, Haghani I.   +9 more
europepmc   +1 more source

Development and Verification of Virtual Population Models for Predicting Drug Pharmacokinetics in Ethnic North American Populations

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1598-1615, October 2025.
ABSTRACT Ethnic variabilities can affect the outcome of drug pharmacokinetics (PK) and drug–drug interactions (DDI). This work aimed to develop four North American (NA) sub‐populations: White, African American, Asian American, and Hispanic_Latino suitable for physiologically based pharmacokinetic (PBPK) modeling and simulations.
Udoamaka Ezuruike, Jean Dinh, Eman El‐Khateeb, Alex Blenkinsop, Oliver Hatley, Iain Gardner   +5 more
wiley   +1 more source

Enhancing antifungal stewardship: The educational and healthcare benefits of involving pharmacy students in audits. [PDF]

Med Mycol
Nguyen DDH, Chau GLL, Reali S, Watts MR, Douglas MW, Beardsley J, Alffenaar JC.   +6 more
europepmc   +1 more source

In vitro evaluation of combination of fluconazole and flucytosine against Cryptococcus neoformans var. neoformans [PDF]

, 1995
Minh Nguyen, Francesco Barchiesi, D A McGough, Victor L. Yu, Michael G. Rinaldi   +4 more
openalex   +1 more source

Assessing Cytochrome P450 Drug Interaction Risk for Dordaviprone Using Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1695-1704, October 2025.
ABSTRACT A physiologically based pharmacokinetic (PBPK) model was developed and verified for dordaviprone, a small molecule with antitumor effects in glioma patients. The model was applied to assess the drug–drug interaction (DDI) potential of dordaviprone as a victim of CYP3A4 inhibitors and inducers, and as a perpetrator of CYP3A4, CYP2C8, CYP2D6 ...
Swati Jaiswal, Nikunjkumar K. Patel, Hannah M. Jones, Savannah McFeely, Shamia L. Faison, Tim Tippin, Odin Naderer   +6 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on the Clinical Efficacy of Azole Antifungals. [PDF]

Genes (Basel)
Singam H, Mossad S.
europepmc   +1 more source

Reversible fluconazole resistance in Candida albicans: a potential in vitro model

, 1997
H M Calvet, Michael R. Yeaman, Scott G. Filler   +2 more
openalex   +1 more source

Antifungal efficacy of caffeic acid and nano-caffeic acid particles against candidiasis: an <i><b>in vitro</b></i> study. [PDF]

J Oral Microbiol
Salehi M, Haghani I, Saeedi M, Morteza-Semnani K, Negarandeh R, Hosseinnataj A, Jafari A, Lotfizadeh A, Rafiei A, Molania T.   +9 more
europepmc   +1 more source

Pharmacokinetics of fluconazole in saliva and plasma after administration of an oral suspension and capsules

, 1996
Cornelis H.W. Koks, P. L. Meenhorst, M. J. X. Hillebrand, A. Bult, Jos H. Beijnen   +4 more
openalex   +1 more source