Results 151 to 160 of about 86,931 (273)
Abstract Introduction Advanced HIV disease (AHD) remains a leading cause of mortality in Latin America and the Caribbean (LAC), driven by late diagnosis, treatment gaps and structural barriers, particularly among key populations and children. Persistent disparities in healthcare access, stigma, and limited health system capacity highlight the need for ...
Evelina Chapman +7 more
wiley +1 more source
Abstract Introduction Despite significant progress in HIV care globally, a persistent 30–40% of people present with advanced HIV disease with ≤200 CD4 cells/µl. The Visitect CD4 Advanced Disease platform is a point‐of‐care CD4 test being implemented in resource‐limited settings.
Elizabeth Nalintya +18 more
wiley +1 more source
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Failure of fluconazole prophylaxis to reduce mortality or the requirement of systemic amphotericin B therapy during treatment for refractory acute myeloid leukemia [PDF]
Wolfgang Kern +9 more
openalex +1 more source
Candida krusei Lung Abscess With Black Necrotic Aspirate
Black, viscous necrotic aspirate from a cavitary lung lesion revealed invasive Candida krusei infection in a patient with advanced HIV. Dark or tar‐like aspirates should prompt evaluation for fungal disease in immunocompromised hosts. ABSTRACT A profoundly immunocompromised man developed a large cavitary lung lesion producing black, viscous aspirate ...
Shan Kai Ing, Pon Ying Lau, Nga Hung Ngu
wiley +1 more source
ABSTRACT Aim Bloodstream infections (BSIs) remain a significant cause of mortality in paediatric intensive care units (PICUs). This study aimed to identify risk factors associated with the aetiology and outcomes of hospital‐acquired BSIs. Methods This retrospective study analysed 422 blood cultures with pathogenic growth collected from patients ...
Vanessa Vicenzi +2 more
wiley +1 more source
Abstract Aims Therapeutic drug monitoring for astronauts faces limitations in conventional blood sampling and sample management onboard the international space station. Here, we explore the feasibility of dried blood spot (DBS) collection during parabolic flights (PF) to overcome these constraints.
Audrey Derobertmasure +8 more
wiley +1 more source
Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2% Fluconazole on Fungal Keratitis [PDF]
Xinying You +3 more
openalex +1 more source
Trichophyton indotineae: Epidemiology, antifungal resistance and antifungal stewardship strategies
There is a concerning trend of widespread and severe superficial fungal infections caused by a new pathogen—Trichophyton indotineae—resistant to standard antifungal therapies. T. indotineae is now spreading globally and evolving. There is increasing urgency for healthcare providers and policy makers to initiate surveillance systems and antifungal ...
Aditya K. Gupta +11 more
wiley +1 more source

