Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira +8 more
wiley +1 more source
Investigation of the effect of gentamicin to fluconazole in fluconazole resistant isolates of candida spp [PDF]
Güncel çalışmalar antifungal ilaç keşfi ve gelişimi antibakteriyel ilaçlara nazaran daha yavaş olduğunu göstermektedir. Antifungal ilaçlara karşı gelişen direnç antifungallerin etkinliğinin azalmasına katkıda bulunmaktadır.
Genç, Bahar
core
Clinical and mycological responses to fluconazole and fluconazole MIC in oropharyngeal candidiasis in HIV-infected patients. [PDF]
INTRODUCTION: OPC is a common opportunistic infection in HIV-infected patients. Although some patients are asymptomatic, progression of the disease may occur leading to esophageal candidiasis.
Pitisuttithum, P +7 more
core
Efficacies of Conventional Antifungals and Complementary and Alternative Medicine as Single or Combination Therapies Against <i>Candida</i> Biofilms in Recurrent Vaginal Candidiasis: An In Vitro Study. [PDF]
Pan Y +12 more
europepmc +1 more source
UPLC-QTOF-MS/MS and Antifungal Activity of a Fraction Enriched in Saponins From Sarcomphalus joazeiro Against Candida spp. [PDF]
da Silva ARP +12 more
europepmc +1 more source
In Vivo Evaluation of a Nanoemulsion-Delivered Chromium(III)-Triazole Complex Against Fluconazole-Resistant <i>Candida albicans</i>. [PDF]
Bedoya-Florez MV +7 more
europepmc +1 more source
A Drug-Drug Interaction of Ainuovirine with Fluconazole in Healthy Adults and Dose Optimization Informed by Pharmacokinetics Modelling. [PDF]
Huang J +9 more
europepmc +1 more source
In vitro antifungal resistance and molecular analysis of the SQLE gene in dermatophytosis: a laboratory-based study. [PDF]
Charlies J +3 more
europepmc +1 more source
Cryptococcal Osteomyelitis in a Virally Suppressed Adolescent Living With HIV: A Case Report. [PDF]
Mandikiyana Chirimuta LA +5 more
europepmc +1 more source

