Results 161 to 170 of about 48,304 (212)

Exposure Matching Using Population Pharmacokinetic Modeling and Simulation to Support Rimegepant Dose Selection for Pediatric Patients With Migraine

open access: yesClinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT Rimegepant is a small molecule calcitonin gene‐related peptide receptor antagonist approved as a 75 mg orally disintegrating tablet for the acute treatment of migraine and the prevention of episodic migraine in adults. A population pharmacokinetic model for oral rimegepant was previously developed using data from 11 phase I studies in adults ...
Craig M. Comisar   +6 more
wiley   +1 more source

Flunitrazepam increases the risk of lamotrigine‐induced cutaneous adverse reactions: Combined analysis of medical big data and clinical research

open access: yesPsychiatry and Clinical Neurosciences, Volume 79, Issue 10, Page 629-635, October 2025.
Aim The concomitant use of lamotrigine and valproic acid, a uridine diphosphate (UDP)‐glucuronosyltransferase inhibitor, is a known risk factor for lamotrigine‐induced rashes, which may develop into fatal or severe cutaneous adverse reactions. No drugs other than valproic acid have been shown to increase lamotrigine concentrations in humans by ...
Hiroshi Bando   +21 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of Saccharomyces cerevisiae NBRC 0203 and Lacticaseibacillus rhamnosus NBRC 3425 as a silage additive for all animal species (EM‐Agriton B.V.)

open access: yesEFSA Journal, Volume 23, Issue 10, October 2025.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the additive consisting of Saccharomyces cerevisiae NBRC 0203 and Lacticaseibacillus rhamnosus NBRC 3425 when used as a technological additive to improve ensiling of all fresh plant material for all animal species at a proposed minimum ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +26 more
wiley   +1 more source

Mutations in <i>TAC1B</i> drive increased <i>CDR1</i> and <i>MDR1</i> expression and azole resistance in <i>Candida auris</i>. [PDF]

open access: yesAntimicrob Agents Chemother
Barker KS   +7 more
europepmc   +1 more source

Correlation of In Vitro Fluconazole Susceptibility with Clinical Outcome for Severely Ill Patients with Oropharyngeal Candidiasis [PDF]

open access: bronze, 1998
Sevtap Arıkan   +6 more
openalex   +1 more source

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