Results 291 to 300 of about 106,245 (320)
Some of the next articles are maybe not open access.
Accumulation of fluconazole in sebum
Int. Journal of Clinical Pharmacology and Therapeutics, 2001Concentrations of fluconazole in sebum and plasma were determined in 2 parallel groups, each consisting of 8 healthy subjects. Group 1 received a 150 mg fluconazole capsule once weekly over a period of 4 weeks, Group 2 was administered 2 capsules/week, corresponding to 300 mg fluconazole/week for 4 weeks. Sampling was performed immediately before and 5
H. Laufen +3 more
openaire +3 more sources
Microbial Drug Resistance, 2017
Fluconazole resistance among clinical Candida parapsilosis isolates is an emerging problem in many countries, including Kuwait. Resistance to fluconazole is mediated by amino acid substitutions in ERG11 and/or by overexpression of efflux pumps MDR1 and ...
M. Asadzadeh +3 more
semanticscholar +1 more source
Fluconazole resistance among clinical Candida parapsilosis isolates is an emerging problem in many countries, including Kuwait. Resistance to fluconazole is mediated by amino acid substitutions in ERG11 and/or by overexpression of efflux pumps MDR1 and ...
M. Asadzadeh +3 more
semanticscholar +1 more source
European Journal of Clinical Pharmacology, 1997
Midazolam is a short-acting benzodiazepine hypnotic extensively metabolized by CYP3A4 enzyme. Orally ingested azole antimycotics, including fluconazole, interfere with the metabolism of oral midazolam during its absorption and elimination phases. We compared the effect of oral and intravenous fluconazole on the pharmacokinetics and pharmacodynamics of ...
Pertti J. Neuvonen +2 more
openaire +3 more sources
Midazolam is a short-acting benzodiazepine hypnotic extensively metabolized by CYP3A4 enzyme. Orally ingested azole antimycotics, including fluconazole, interfere with the metabolism of oral midazolam during its absorption and elimination phases. We compared the effect of oral and intravenous fluconazole on the pharmacokinetics and pharmacodynamics of ...
Pertti J. Neuvonen +2 more
openaire +3 more sources
Clinical Pharmacokinetics of Fluconazole
Clinical Pharmacokinetics, 1993Fluconazole was recently developed for the treatment of superficial and systemic fungal infections. Triazole groups and insertion of 2 fluoride atoms increase the polarity and hydrosolubility of the drug, allowing it to be used in a parenteral form. Bioassay methods using Candida pseudotropicalis as a test organism were the first techniques used for ...
Jean-Philippe Ryckelynck +1 more
openaire +2 more sources
Fluconazole use and safety in the nursery
Early Human Development, 2012Fluconazole is a triazole antifungal agent that is widely used in the nursery. It is available in both intravenous and oral formulation, and is active against most of the fungal pathogens that require treatment when retrieved from culture samples in neonatal intensive care units.
E. Castagnola +7 more
openaire +3 more sources
Treatment of Coccidioidal Meningitis with Fluconazole
Clinical Infectious Diseases, 1990Fluconazole was administered at doses of 50-400 mg/d to 18 patients (15 men, three women) with coccidioidal meningitis. After a mean duration of treatment of 9.8 months, 10 (67%) of 15 assessable patients had responded, one (7%) of 15 had partially responded, and four (27%) of 15 had not responded to therapy.
Tucker, R.M. +10 more
openaire +3 more sources
FLUCONAZOLE THERAPY IN NEONATAL CANDIDEMIA
American Journal of Perinatology, 2000We reviewed 62 episodes (from 59 infants) of neonatal candidemia that occurred between January 1994 and June 1999. Except 5 term babies, all infants were premature (median gestational age [GA], 30 weeks) and birth weight was less than 2,500 g (median, 1,300 g). Most infants had reported risk factors and other neonatal problems.
Huang, Yhu-Chering +6 more
openaire +2 more sources
Developmental and transplacental genotoxicology: Fluconazole
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2008Over the last 40 years mankind has been facing new types of radiochemical environmental settings with every decade. During the last decade, biomonitoring was additionally focused on assessing associations between environmental exposure(s) and both early and late biological effects in children.
Boris Mildner +9 more
openaire +3 more sources