Results 101 to 110 of about 310,218 (255)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The Evaluation of Enhanced Academic Instruction in After-School Programs: Findings After the First Year of Implementation [PDF]

, 2008
This report presents one-year implementation and impact findings on two supplemental academic instruction approaches developed for after-school settings -- one for math and one for reading. Compared with regular after-school programming, the supplemental
Alison Rebeck Black, Fred Doolittle, Jean Baldwin Grossman, Pei Zhu, Rebecca Unterman   +4 more
core  

The contributions of domain-general and numerical factors to third-grade arithmetic skills and mathematical learning disability [PDF]

, 2014
Explanations of the marked individual differences in elementary school mathematical achievement and mathematical learning disability (MLD or dyscalculia) have involved domain-general factors (working memory, reasoning, processing speed and oral language)
Cowan, Richard, Powell, Daisy
core   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A single-system account of the relationship between priming, recognition, and fluency. [PDF]

, 2008
A single-system computational model of priming and recognition was applied to studies that have looked at the relationship between priming, recognition, and fluency in continuous identification paradigms.
Berry, CJ, Henson, RN, Shanks, DR
core   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Shifting gear in the study of the bilingual advantage : language switching examined as a possible moderator [PDF]

, 2019
The bilingual advantage is a heavily debated topic in research on bilingualism. The current study further investigated one specific aspect of bilingualism proposed to be a determining factor for the bilingual advantage, namely language switching ...
Struys, Esli, Van Herck, Shauni, Woumans, Evy   +2 more
core   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Verbal and non-verbal fluency in adults with developmental dyslexia: Phonological processing or executive control problems? [PDF]

, 2017
The executive function of fluency describes the ability to generate items according to specific rules. Production of words beginning with a certain letter (phonemic fluency) is impaired in dyslexia, whilst generation of words belonging to a certain ...
Andrés, Ardila, Ardila, Bacon, Benton, Booth, Borkowski, Bousfield, Brachacki, Brosnan, Brunswick, Castles, Cohen, Crowe, Delis, Fawcett, Felton, Felton, Finucci, Fisk, Frith, Griffiths, Hatcher, Henry, Henry, Hurks, Kinsbourne, Landerl, Levin, Luo, Lyon, Marzocchi, Mayr, McLoughlin, Menghini, Mervis, Mielnik, Miller-Shaul, Miyake, Miyake, Moore, Moura, Newcombe, Nicolson, Pennington, Phillips, Plaza, Plaza, Rabbitt, Regard, Reid, Reiter, Rosen, Ruff, Ruff, Shallice, Shao, Siegel, Smith-Spark, Smith-Spark, Smith-Spark, Snowling, Stuss, Torgeson, Troyer, Troyer, Turner, Varvara, Vellutino, Vellutino, Wechsler, Wechsler, Wilson   +72 more
core   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source